Introduction：Basic information about CAS 65-64-5|mebanazine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | mebanazine |
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| CAS Number | 65-64-5 | Molecular Weight | 136.194 |
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| Density | 1.0±0.1 g/cm3 | Boiling Point | 262.1±19.0 °C at 760 mmHg |
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| Molecular Formula | C8H12N2 | Melting Point | / |
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| MSDS | / | Flash Point | 129.6±25.1 °C |
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Names
| Name | 1-phenylethylhydrazine |
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| Synonym | More Synonyms |
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mebanazine BiologicalActivity
| Description | Mebanazine is a potent monoamine oxidase (MAO) inhibitor. Mebanazine can be used in research of depression[1]. |
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| Related Catalog | Signaling Pathways >>Neuronal Signaling >>Monoamine OxidaseResearch Areas >>Neurological Disease |
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| In Vivo | Mebanazine (90 mg/kg; i.p.; once; mature female rats) decreases the blood giucose level[1]. Mebanazine (1-60 mg/kg; i.p.; once; mature female rats) has the minimal dose which lowered blood glucose after 12 h is 60 mg/kg[1]. Animal Model: Mature female rats[1] Dosage: 90 mg/kg Administration: Intraperitoneal injection; once Result: Decreased the blood giucose level after 4-8 h, and continues for 2 days. Animal Model: Mature female rats[1] Dosage: 0-60 mg/kg Administration: Intraperitoneal injection; once Result: Decreased the blood giucose level in a dose-dependent manner. |
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| References | [1]. Mishkinsky UZ, et. al. The hypoglycaemic effect of mebanazine (Actomol) and its mechanism. Biochemical Pharmacology. 1965;14(7):1059-64. |
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Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
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| Boiling Point | 262.1±19.0 °C at 760 mmHg |
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| Molecular Formula | C8H12N2 |
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| Molecular Weight | 136.194 |
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| Flash Point | 129.6±25.1 °C |
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| Exact Mass | 136.100052 |
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| PSA | 38.05000 |
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| LogP | 1.07 |
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| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
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| Index of Refraction | 1.546 |
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| InChIKey | HHRZAEJMHSGZNP-UHFFFAOYSA-N |
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| SMILES | CC(NN)c1ccccc1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- MV5650000
- CHEMICAL NAME :
- Hydrazine, (alpha-methylbenzyl)-
- CAS REGISTRY NUMBER :
- 65-64-5
- LAST UPDATED :
- 198812
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C8-H12-N2
- MOLECULAR WEIGHT :
- 136.22
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 225 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 238,62,1960
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Safety Information
| RIDADR | UN 1851 |
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| Packaging Group | III |
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| Hazard Class | 6.1(b) |
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| HS Code | 2928000090 |
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Customs
| HS Code | 2928000090 |
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| Summary | 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0% |
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Synonyms
| EINECS 200-615-6 |
| Mebanazina [INN-Spanish] |
| a-Methylbenzylhydrazine |
| actamol |
| mebanazine |
| Phenylethylhydrazine |
| Mebenazine |
| 1-(1-phenylethyl)hydrazine |
| Hydrazine, (1-phenylethyl)- |
| (+/-)-(1-Phenylethyl)hydrazin |
| Actomol |
| Mebanazinum [INN-Latin] |
| (1-Phenylethyl)hydrazine |
| a-Phenethyl Hydrazine |
