CAS 133868-46-9|valnemulin Hydrochloride

Introduction：Basic information about CAS 133868-46-9|valnemulin Hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. valnemulin Hydrochloride BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Articles1
6. Synonyms

Common Name	valnemulin Hydrochloride
CAS Number	133868-46-9	Molecular Weight	601.281
Density	/	Boiling Point	672.7ºC at 760 mmHg
Molecular Formula	C₃₁H₅₃ClN₂O₅S	Melting Point	/
MSDS	ChineseUSA	Flash Point	360.6ºC

Names

Name	Valnemulin hydrochloride
Synonym	More Synonyms

valnemulin Hydrochloride BiologicalActivity

Description	Valnemulin hydrochloride is a pleuromutilin antibiotic which inhibits protein synthesis in bacteria by binding the peptidyl transferase enzyme in the 50s ribosomal subunit.
Related Catalog	Signaling Pathways >>Anti-infection >>BacterialResearch Areas >>Others
References	[1]. L. Stipkovits, et al. The efficacy of valnemulin (Econor®) in the control of disease caused by experimental infection of calves with Mycoplasma bovis. Research in Veterinary Science, Volume 78, Issue 3, June 2005, Pages 207–215.

Chemical & Physical Properties

Boiling Point	672.7ºC at 760 mmHg
Molecular Formula	C₃₁H₅₃ClN₂O₅S
Molecular Weight	601.281
Flash Point	360.6ºC
Exact Mass	600.336365
PSA	144.02000
LogP	6.39740
InChIKey	MFBPRQKHDIVLOJ-UHFFFAOYSA-N
SMILES	C=CC1(C)CC(OC(=O)CSC(C)(C)CNC(=O)C(N)C(C)C)C2(C)C(C)CCC3(CCC(=O)C32)C(C)C1O.Cl
Storage condition	0-6°C

Safety Information

RIDADR	NONH for all modes of transport

Articles1

Mutations in the 50S ribosomal subunit of Brachyspira hyodysenteriae associated with altered minimum inhibitory concentrations of pleuromutilins.

Vet. Microbiol. 172(1-2) , 223-9, (2014)

Brachyspira hyodysenteriae, the causative agent of swine dysentery, is responsible for severe mucohaemorrhagic colitis with considerable financial loss to worldwide swine production. Antimicrobial res...

Synonyms

Acetic acid, 2-[[2-[[(2R)-2-amino-3-methyl-1-oxobutyl]amino]-1,1-dimethylethyl]thio]-, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester, hydrochloride (1:1)

UNII-W1GDP58BNQ

Econor

Valnemulin hydrochloride

S4216

(1S,2R,3S,4S,6R,7R,8R,14R)-3-Hydroxy-2,4,7,14-tetramethyl-9-oxo-4-vinyltricyclo[5.4.3.0]tetradec-6-yl {[2-methyl-1-(D-valylamino)-2-propanyl]sulfanyl}acetate hydrochloride (1:1)

Valnemulin HCl

Valnemulin (Hydrochloride)

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