Introduction：Basic information about CAS 137235-80-4|Fibrinogen-Binding Peptide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Fibrinogen-Binding Peptide |
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| CAS Number | 137235-80-4 | Molecular Weight | 565.62 |
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| Density | 1.343 g/cm3 | Boiling Point | 1067.8ºC at 760 mmHg |
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| Molecular Formula | C25H39N7O8 | Melting Point | / |
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| MSDS | / | Flash Point | 599.6ºC |
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Names
| Name | (4S)-4-amino-5-[[(2S)-1-[[(2S,3S)-1-[(2S)-2-[[(1S)-1-carboxyethyl]carbamoyl]pyrrolidin-1-yl]-3-methyl-1-oxopentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid |
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| Synonym | More Synonyms |
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Fibrinogen-Binding Peptide BiologicalActivity
| Description | Fibrinogen-Binding Peptide (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide binds fibrinogen and inhibits both the adhesion of platelets to fibrinogen and platelet aggregation, and also inhibits the adhesion of platelets to vitronectin[1]. |
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| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>Others |
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| References | [1]. Gartner TK, et al. The peptide Glu-His-Ile-Pro-Ala binds fibrinogen and inhibits platelet aggregation and adhesion to fibrinogen and vitronectin. Proc Soc Exp Biol Med. 1991 Oct;198(1):649-55. |
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Chemical & Physical Properties
| Density | 1.343 g/cm3 |
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| Boiling Point | 1067.8ºC at 760 mmHg |
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| Molecular Formula | C25H39N7O8 |
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| Molecular Weight | 565.62 |
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| Flash Point | 599.6ºC |
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| Exact Mass | 565.28600 |
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| PSA | 236.91000 |
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| LogP | 0.55120 |
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| Vapour Pressure | 0mmHg at 25°C |
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| Index of Refraction | 1.577 |
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| InChIKey | VWJLJHZPMZGDDV-HOCDWTQPSA-N |
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| SMILES | CCC(C)C(NC(=O)C(Cc1cnc[nH]1)NC(=O)C(N)CCC(=O)O)C(=O)N1CCCC1C(=O)NC(C)C(=O)O |
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Synonyms
| (4S)-4-amino-5-[[(2S)-1-[[(2S,3S)-1-[(2S)-2-[[(2S)-1-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-methyl-1-oxopentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid |
| Glutamyl-histidyl-isoleucyl-prolyl-alanine |
| Glu-his-ile-pro-ala |
