CAS 130104-32-4|Eberconazole nitrate

Introduction:Basic information about CAS 130104-32-4|Eberconazole nitrate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameEberconazole nitrate
CAS Number130104-32-4Molecular Weight392.236
Density/Boiling Point495ºC at 760 mmHg
Molecular FormulaC18H15Cl2N3O3Melting Point/
MSDS/Flash Point253.2ºC

Names

Name1-(1,3-dichloro-6,11-dihydro-5H-dibenzo[1,2-a:1',4'-e][7]annulen-11-yl)imidazole,nitric acid
SynonymMore Synonyms

Eberconazole nitrate BiologicalActivity

DescriptionEberconazole nitrate is a dichlorinated imidazole derivative with antifungal activity. Eberconazole nitrate is more active than Clotrimazole, Ketoconazole, and Miconazole. Eberconazole nitrate has the potential for the research of dermatophytoses with a topical administration[1].
Related CatalogResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>Fungal
References

[1]. Fernández-Torres B, et al. In vitro activities of the new antifungal drug eberconazole and three other topical agents against 200 strains of dermatophytes. J Clin Microbiol. 2003;41(11):5209-5211.

Chemical & Physical Properties

Boiling Point495ºC at 760 mmHg
Molecular FormulaC18H15Cl2N3O3
Molecular Weight392.236
Flash Point253.2ºC
Exact Mass391.049042
PSA83.87000
LogP5.10170
Vapour Pressure1.86E-09mmHg at 25°C
InChIKeyDPHMSVRBAXJSPF-UHFFFAOYSA-N
SMILESClc1cc(Cl)c2c(c1)CCc1ccccc1C2n1ccnc1.O=[N+]([O-])O

Synonyms

1H-Imidazole, 1-(2,4-dichloro-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-, nitrate (1:1)
1-(2,4-Dichloro-10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-1H-imidazole nitrate (1:1)
Eberconazole nitrate
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