Introduction：Basic information about CAS 895542-09-3|Trifarotene, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Trifarotene |
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| CAS Number | 895542-09-3 | Molecular Weight | 459.577 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 641.9±55.0 °C at 760 mmHg |
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| Molecular Formula | C29H33NO4 | Melting Point | / |
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| MSDS | / | Flash Point | 342.0±31.5 °C |
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Names
| Name | 4-[3-(3-tert-butyl-4-pyrrolidin-1-ylphenyl)-4-(2-hydroxyethoxy)phenyl]benzoic acid |
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| Synonym | More Synonyms |
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Trifarotene BiologicalActivity
| Description | Trifarotene is a retinoic acid receptor (RAR) agonist with Kdapp of 2, 15 and 500 nM for RARγ, RARβ and RARα, respectively. |
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| Related Catalog | Signaling Pathways >>Metabolic Enzyme/Protease >>RAR/RXRResearch Areas >>Inflammation/Immunology |
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| Target | Kdapp: 2 nM (RARγ), 15 nM (RARβ), 500 nM (RARα)[1] |
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| References | [1]. Thibaud Biadatti, et al. Novel ligands that modulate rar receptors, and use thereof in human medicine and in cosmetics. WO 2006066978 A1. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 641.9±55.0 °C at 760 mmHg |
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| Molecular Formula | C29H33NO4 |
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| Molecular Weight | 459.577 |
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| Flash Point | 342.0±31.5 °C |
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| Exact Mass | 459.240967 |
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| PSA | 70.00000 |
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| LogP | 6.27 |
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| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
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| Index of Refraction | 1.599 |
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| InChIKey | MFBCDACCJCDGBA-UHFFFAOYSA-N |
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| SMILES | CC(C)(C)c1cc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCO)ccc1N1CCCC1 |
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| Storage condition | 2-8℃ |
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Synonyms
| 4'-(2-Hydroxyethoxy)-3''-(2-methyl-2-propanyl)-4''-(1-pyrrolidinyl)-1,1':3',1''-terphenyl-4-carboxylic acid |
| [1,1':3',1''-Terphenyl]-4-carboxylic acid, 3''-(1,1-dimethylethyl)-4'-(2-hydroxyethoxy)-4''-(1-pyrrolidinyl)- |
| Trifarotene |
| CD5789 |
| UNII-0J8RN2W0HK |
