CAS 131-48-6|N-Acetylneuraminic acid
| Common Name | N-Acetylneuraminic acid | ||
|---|---|---|---|
| CAS Number | 131-48-6 | Molecular Weight | 309.270 |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 762.3±60.0 °C at 760 mmHg |
| Molecular Formula | C11H19NO9 | Melting Point | 184-186 °C (dec.)(lit.) |
| MSDS | ChineseUSA | Flash Point | 414.8±32.9 °C |
Names
| Name | N-acetylneuraminic acid |
|---|---|
| Synonym | More Synonyms |
N-Acetylneuraminic acid BiologicalActivity
| Description | N-Acetylneuraminic acid is a nine-carbon, sialic acid monosaccharide commonly found in glycoproteins on cell membranes and in glycolipids such as gangliosides in mammalian cells. Studies suggest that N-Acetylneuraminic acid is useful biologically in neurotransmission, leukocyte extravasation, viral or bacterial infections and carbohydrate-protein recognition. |
|---|---|
| Related Catalog | Research Areas >>Cardiovascular DiseaseNatural Products >>Others |
| Target | Human Endogenous Metabolite |
| References | [1]. Bondioli L et al. PLGA nanoparticles surface decorated with the sialic acid, N-acetylneuraminic acid. Biomaterials. 2010 Apr;31(12):3395-403. [2]. Bondioli L et al. PLGA nanoparticles surface decorated with the sialic acid, N-acetylneuraminic acid. Biomaterials. 2010 Apr;31(12):3395-403. |
Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 762.3±60.0 °C at 760 mmHg |
| Melting Point | 184-186 °C (dec.)(lit.) |
| Molecular Formula | C11H19NO9 |
| Molecular Weight | 309.270 |
| Flash Point | 414.8±32.9 °C |
| Exact Mass | 309.105988 |
| PSA | 176.78000 |
| LogP | -3.98 |
| Vapour Pressure | 0.0±5.8 mmHg at 25°C |
| Index of Refraction | 1.581 |
| InChIKey | SQVRNKJHWKZAKO-LUWBGTNYSA-N |
| SMILES | CC(=O)NC1C(O)CC(O)(C(=O)O)OC1C(O)C(O)CO |
| Water Solubility | 50 g/L (20 ºC) |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2932999099 |
Customs
| HS Code | 2932999099 |
|---|---|
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles104
More Articles| Antiviral effect of methylated flavonol isorhamnetin against influenza. PLoS ONE 10(3) , e0121610, (2015) Influenza is an infectious respiratory disease with frequent seasonal epidemics that causes a high rate of mortality and morbidity in humans, poultry, and animals. Influenza is a serious economic conc... | |
| Pathogenicity and transmissibility of novel reassortant H3N2 influenza viruses with 2009 pandemic H1N1 genes in pigs. J. Virol. 89(5) , 2831-41, (2015) At least 10 different genotypes of novel reassortant H3N2 influenza viruses with 2009 pandemic H1N1 [A(H1N1)pdm09] gene(s) have been identified in U.S. pigs, including the H3N2 variant with a single A... | |
| Sialidases as regulators of bioengineered cellular surfaces. Glycobiology 25 , 784-91, (2015) Human sialidases (NEUs) catalyze the removal of N-acetyl neuraminic acids from the glycome of the cell and regulate a diverse repertoire of nominal cellular functions, such as cell signaling and adhes... |
Synonyms
| 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic acid |
| NANA |
| 5-(acetylamino)-3,5-dideoxy-δ-glycero-δ-galacto-2-Nonulosonic acid |
| NANA H2O |
| Sialomucin |
| sialic acid powder |
| Lactaminic acid |
| 5-Acetamido-3,5-dideoxy-D-glycero-D-galactononulosonic acid |
| N-acetyl-D-neuraminic acid |
| 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic acid |
| 5-Acetamido-3,5-dideoxy-D-glycero-D-galactononulosonic acid,Lactaminic acid,NAN |
| O-SIALIC ACID |
| NANA TYPE IV-S |
| NEU5AC |
| D-glycero-D-galacto-2-Nonulosonic acid, 5-(acetylamino)-3,5-dideoxy- |
| sialic acid |
| NANA TYPE VI |
| EINECS 205-023-1 |
| 5-(Acetylamino)-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic Acid |
| NAN |
| (4S,5R,6R,7S,8R)-5-Acetamido-4,6,7,8,9-pentahydroxy-2-oxononanoic acid |
| Aceneuramic acid |
| N-Acetylneuraminic acid |
| MFCD00006620 |
