CAS 13367-85-6|Prostaglandin B2
| Common Name | Prostaglandin B2 | ||
|---|---|---|---|
| CAS Number | 13367-85-6 | Molecular Weight | 334.45 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 537.0±50.0 °C at 760 mmHg |
| Molecular Formula | C20H30O4 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 292.6±26.6 °C |
| Symbol | GHS02, GHS07 | Signal Word | Danger |
Names
| Name | prostaglandin B2 |
|---|---|
| Synonym | More Synonyms |
Prostaglandin B2 BiologicalActivity
| Description | Prostaglandin B2 is a prostaglandin. Prostaglandin B2 is the main substance in cord blood mesenchymal stem cells, to inhibit DC-T Cell proliferation. Prostaglandin B2 also induces cutaneous vasoconstriction of the canine hind paw[1][2]. |
|---|---|
| Related Catalog | Research Areas >>Cardiovascular DiseaseResearch Areas >>Endocrinology |
| Target | Human Endogenous Metabolite |
| References | [1]. Greenberg S, Engelbrecht JA, Wilson WR. Prostaglandin B2-induced cutaneous vasoconstriction of the canine hind paw. Circ Res. 1974 Apr;34(4):491-7. [2]. van den Berk LC, et al. Cord blood mesenchymal stem cells suppress DC-T Cell proliferation via prostaglandin B2. Stem Cells Dev. 2014 Jul 15;23(14):1582-93. |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 537.0±50.0 °C at 760 mmHg |
| Molecular Formula | C20H30O4 |
| Molecular Weight | 334.45 |
| Flash Point | 292.6±26.6 °C |
| Exact Mass | 334.214417 |
| PSA | 74.60000 |
| LogP | 3.24 |
| Appearance of Characters | solution |
| Vapour Pressure | 0.0±3.2 mmHg at 25°C |
| Index of Refraction | 1.564 |
| InChIKey | PRFXRIUZNKLRHM-HKVRTXJWSA-N |
| SMILES | CCCCCC(O)C=CC1=C(CC=CCCCC(=O)O)C(=O)CC1 |
| Storage condition | −20°C |
| Water Solubility | ethanol: ~100 mg/mL |
Safety Information
| Symbol | GHS02, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H225-H319-H336 |
| Supplemental HS | Repeated exposure may cause skin dryness or cracking. |
| Precautionary Statements | P210-P280-P304 + P340 + P312-P305 + P351 + P338-P337 + P313-P403 + P235 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn,Xi,F |
| Risk Phrases | 20/21/22-67-66-36-11 |
| Safety Phrases | 36/37-26 |
| RIDADR | UN 1231 3/PG 2 |
| WGK Germany | 3 |
Articles31
More Articles| Identification of prostamides, fatty acyl ethanolamines, and their biosynthetic precursors in rabbit cornea. J. Lipid Res. 56 , 1419-33, (2015) Arachidonoyl ethanolamine (anandamide) and pros-taglandin ethanolamines (prostamides) are biologically active derivatives of arachidonic acid. Although available through different precursor phospholip... | |
| Differences in the Neuroprotective Effect of Orally Administered Virgin Olive Oil (Olea europaea) Polyphenols Tyrosol and Hydroxytyrosol in Rats. J. Agric. Food Chem. 63 , 5957-63, (2015) The neuroprotective effect of virgin olive oil (VOO) polyphenols has been related to their antioxidant effect. The main objective was to analyze how tyrosol and hydroxytyrosol contribute to the antiox... | |
| Cord blood mesenchymal stem cells suppress DC-T Cell proliferation via prostaglandin B2. Stem Cells Dev. 23(14) , 1582-93, (2014) Immune suppression is a very stable property of multipotent stromal cells also known as mesenchymal stem cells (MSCs). All cell lines tested showed robust immune suppression not affected by a long cul... |
Synonyms
| (5Z,13E,15R)-15-Hydroxy-9-oxoprosta-5,8(12),13-trien-1-oic acid |
| MFCD00065730 |
| EINECS 234-237-8 |
| Prostaglandin B2 |
| (5Z,13E,15S)-15-Hydroxy-9-oxoprosta-5,8(12),13-trien-1-oic acid PGB2 |
| Prosta-5,8(12),13-trien-1-oic acid, 15-hydroxy-9-oxo-, (5Z,13E,15R)- |
