Introduction：Basic information about CAS 132-89-8|Chlorthenoxazine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Chlorthenoxazine |
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| CAS Number | 132-89-8 | Molecular Weight | 211.64500 |
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| Density | 1.253g/cm3 | Boiling Point | 449.8ºC at 760mmHg |
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| Molecular Formula | C10H10ClNO2 | Melting Point | / |
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| MSDS | / | Flash Point | 225.8ºC |
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Names
| Name | 2-(2-chloroethyl)-2,3-dihydro-1,3-benzoxazin-4-one |
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| Synonym | More Synonyms |
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Chlorthenoxazine BiologicalActivity
| Description | Chlorthenoxazine is a nonsteroidal anti-inflammatory drug. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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Chemical & Physical Properties
| Density | 1.253g/cm3 |
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| Boiling Point | 449.8ºC at 760mmHg |
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| Molecular Formula | C10H10ClNO2 |
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| Molecular Weight | 211.64500 |
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| Flash Point | 225.8ºC |
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| Exact Mass | 211.04000 |
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| PSA | 38.33000 |
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| LogP | 2.09260 |
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| Vapour Pressure | 2.78E-08mmHg at 25°C |
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| Index of Refraction | 1.541 |
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| InChIKey | YEKMWXFHPZBZLR-UHFFFAOYSA-N |
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| SMILES | O=C1NC(CCCl)Oc2ccccc21 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DM3675000
- CHEMICAL NAME :
- 4H-1,3-Benzoxazin-4-one, 2-(2-chloroethyl)-2,3-dihydro-
- CAS REGISTRY NUMBER :
- 132-89-8
- BEILSTEIN REFERENCE NO. :
- 0170863
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C10-H10-Cl-N-O2
- MOLECULAR WEIGHT :
- 211.66
- WISWESSER LINE NOTATION :
- T66 BVM EO DHJ D2G
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10 gm/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - coma
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,651,1957
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 730 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 1,36,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 11155 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 13,884,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1702 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 13,884,1963
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Safety Information
Customs
| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 2-(2-chloro-ethyl)-2,3-dihydro-benz[e][1,3]oxazin-4-one |
| 2-(2-chloro-ethyl)-2,3-dihydro-benzo[e][1,3]oxazin-4-one |
| Chlorethylbenzmethoxazone |
| Ossipirina |
| EINECS 205-082-3 |
| Ossazone |
| Reumagrip |
| Reugaril |
| Apirazin |
| 2-(2-Chlor-aethyl)-2,3-dihydro-benz[e][1,3]oxazin-4-on |
| chlorothenoxazine |
| Valmorin |
| Valtorin |
| Chlorthenoxazin |
| chlorthenoxazine |
