CAS 135046-48-9|(+)-Clopidogrel bisulfate

Introduction:Basic information about CAS 135046-48-9|(+)-Clopidogrel bisulfate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name(+)-Clopidogrel bisulfate
CAS Number135046-48-9Molecular Weight419.900
Density/Boiling Point423.7ºC at 760 mmHg
Molecular FormulaC16H18ClNO6S2Melting Point184ºC
MSDSUSAFlash Point210ºC

Names

Name(S)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate
SynonymMore Synonyms

(+)-Clopidogrel bisulfate BiologicalActivity

DescriptionClopidogrel sulfate is an antiplatelet agent. Specifically, Clopidogrel sulfate inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. Clopidogrel sulfate can be used for research of heart disease and stroke[1].
Related CatalogResearch Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>Others
References

[1]. Pindelska E, et al. Solid-state NMR as an effective method of polymorphic analysis: solid dosage forms of clopidogrel hydrogensulfate. J Pharm Sci. 2015 Jan;104(1):106-13.  

Chemical & Physical Properties

Boiling Point423.7ºC at 760 mmHg
Melting Point184ºC
Molecular FormulaC16H18ClNO6S2
Molecular Weight419.900
Flash Point210ºC
Exact Mass419.026398
PSA140.76000
LogP4.03980
Vapour Pressure8.71E-09mmHg at 25°C
InChIKeyFDEODCTUSIWGLK-UHFFFAOYSA-N
SMILESCOC(=O)C(c1ccccc1Cl)N1CCc2sccc2C1.O=S(=O)(O)O
Storage condition2-8°C

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard CodesT+
Safety Phrases22-24/25
RIDADRNONH for all modes of transport
HS Code2934999090

Customs

HS Code2934999090
Summary2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

MFCD00876395
Plavix
Clopidogrel Hydrogen sulfate
Methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate
methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoate sulfate
methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoate sulfate (1:1)
Clopidogrel bisulfate
(2S)-(2-chlorophényl)(6,7-dihydrothiéno[3,2-c]pyridin-5(4H)-yl)éthanoate de méthyle sulfate
Clopidogrel Hydrogensulfate
Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (αS)-, sulfate (1:1)
(+)-Clopidogrel hydrogen sulfate
Clopidogrel bisulphate
(S)-(+)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetate bisulfate
Methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate (1:1)
a-(S)-(2-Chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetic Acid Methyl Ester Sulfate (1:1)
Methyl aS-(2-Chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetate Sulfate (1:1)
Methyl-(2S)-(2-chlorphenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoatsulfat
S-(+)-Clopidogrel Hydrogen Sulfate
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