Introduction：Basic information about CAS 362049-50-1|2'-Deoxy-2'-fluorouridine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2'-Deoxy-2'-fluorouridine |
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| CAS Number | 362049-50-1 | Molecular Weight | 246.192 |
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| Density | 1.6±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C9H9D2FN2O5 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 2'-fluorodeoxyuridine-5,6-d2 |
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| Synonym | More Synonyms |
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2'-Deoxy-2'-fluorouridine BiologicalActivity
| Description | 2'-Deoxy-2'-fluorouridine-d2 is the deuterium labeled 2'-Deoxy-2'-fluorouridine[1]. 2'-Deoxy-2'-fluorouridine can be used as an intermediate for antiinfluenza virus agents synthesis[2]. |
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| Related Catalog | Signaling Pathways >>Anti-infection >>Influenza VirusResearch Areas >>Infection |
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| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
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| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. J V Tuttle, et al. Purine 2'-deoxy-2'-fluororibosides as antiinfluenza virus agents. J Med Chem |
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Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
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| Molecular Formula | C9H9D2FN2O5 |
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| Molecular Weight | 246.192 |
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| Exact Mass | 246.065201 |
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| PSA | 104.55000 |
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| LogP | -1.31 |
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| Index of Refraction | 1.608 |
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| InChIKey | UIYWFOZZIZEEKJ-SXFMXZDVSA-N |
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| SMILES | O=c1ccn(C2OC(CO)C(O)C2F)c(=O)[nH]1 |
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Synonyms
| 2'-Deoxy-2'-fluorouridine |
| Uridine, 2'-deoxy-2'-fluoro- |
| 2'-Fluoro-2'-deoxyuridine |
