Introduction：Basic information about CAS 189639-09-6|9-CP-Ade mesylate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 9-CP-Ade mesylate |
|---|
| CAS Number | 189639-09-6 | Molecular Weight | 299.34900 |
|---|
| Density | / | Boiling Point | 440.5ºC at 760 mmHg |
|---|
| Molecular Formula | C11H17N5O3S | Melting Point | 180-183ºC(lit.) |
|---|
| MSDS | ChineseUSA | Flash Point | 220.2ºC |
|---|
Names
| Name | 9-Cyclopentyladenine monomethanesulfonate |
|---|
| Synonym | More Synonyms |
|---|
9-CP-Ade mesylate BiologicalActivity
| Description | 9-Cyclopentyladenine monomethylsulfonate (9-CP-Ade mesylate) is a stable non-competitive adenylate cyclase inhibitor with cell permeable properties[1][2]. |
|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>GPCR/G Protein >>Adenylate CyclaseResearch Areas >>Neurological Disease |
|---|
| In Vitro | 9-Cyclopentyladenine monomethanesulfonate (200 μM, 30 min) inhibits the activation of cAMP response element binding protein (CREB) and completely blocks neurogenesis in PC12 cells[1]. 9-Cyclopentyladenine monomethanesulfonate (100 μM, 30min) attenuates the effect of relaxin on mechanical activity and prevents relaxin-induced hyperpolarization thereby being involved in the regulation of relaxin on ileal smooth muscle activity in female CD1 Swiss mice[2]. 9-Cyclopentyladenine monomethanesulfonate (100 μM, 6 hours) promotes restoration of the keratinocyte permeability barrier by inhibiting the synthesis of cAMP in male hairless mice[3]. |
|---|
| References | [1]. Ulrike Riese，et al. Militarinone A induces differentiation in PC12 cells via MAP and Akt kinase signal transduction pathways. FEBS Lett. 2004 Nov 19;577(3):455-9. [2]. Eglantina Idrizaj，et al. Relaxin influences ileal muscular activity through a dual signaling pathway in mice. World J Gastroenterol. 2018 Feb 28;24(8):882-893. [3]. Mitsuhiro Denda, et al. Association of cyclic adenosine monophosphate with permeability barrier homeostasis of murine skin. J Invest Dermatol. 2004 Jan;122(1):140-6. |
|---|
Chemical & Physical Properties
| Boiling Point | 440.5ºC at 760 mmHg |
|---|
| Melting Point | 180-183ºC(lit.) |
|---|
| Molecular Formula | C11H17N5O3S |
|---|
| Molecular Weight | 299.34900 |
|---|
| Flash Point | 220.2ºC |
|---|
| Exact Mass | 299.10500 |
|---|
| PSA | 132.37000 |
|---|
| LogP | 2.68960 |
|---|
| Vapour Pressure | 5.85E-08mmHg at 25°C |
|---|
| InChIKey | AJMDRSJHCYQPQI-UHFFFAOYSA-N |
|---|
| SMILES | CS(=O)(=O)O.Nc1ncnc2c1ncn2C1CCCC1 |
|---|
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|
| RIDADR | NONH for all modes of transport |
|---|
| RTECS | AU6255000 |
|---|
Synonyms
| 9-cyclopentylpurin-6-amine,methanesulfonic acid |
| 9-CP-Ade mesylate 9-Cyclopentyladenine mesylate |
