CAS 348086-66-8|Proteasome Substrate II

Introduction：Basic information about CAS 348086-66-8|Proteasome Substrate II, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Proteasome Substrate II BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Proteasome Substrate II
CAS Number	348086-66-8	Molecular Weight	664.745
Density	1.3±0.1 g/cm3	Boiling Point	967.8±65.0 °C at 760 mmHg
Molecular Formula	C₃₅H₄₄N₄O₉	Melting Point	/
MSDS	ChineseUSA	Flash Point	539.1±34.3 °C

Names

Name	z-leu-leu-glu-amc
Synonym	More Synonyms

Proteasome Substrate II BiologicalActivity

Description	Z-Leu-Leu-Glu-AMC is a substrate peptide, and can be used for determination of postacidic-like hydrolysing activity of 20S proteasome[1]
Related Catalog	Research Areas >>OthersSignaling Pathways >>Metabolic Enzyme/Protease >>Proteasome
References	[1]. McNaught KS, et al. Proteasomal function is impaired in substantia nigra in Parkinson's disease. Neurosci Lett. 2001 Jan 19;297(3):191-4.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	967.8±65.0 °C at 760 mmHg
Molecular Formula	C₃₅H₄₄N₄O₉
Molecular Weight	664.745
Flash Point	539.1±34.3 °C
Exact Mass	664.310852
PSA	193.14000
LogP	5.74
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.578
InChIKey	FOYHOBVZPWIGJM-KCHLEUMXSA-N
SMILES	Cc1cc(=O)oc2cc(NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCc3ccccc3)ccc12

Safety Information

Safety Phrases	22-24/25
WGK Germany	3

Synonyms

Z-LEU-LEU-GLU-7-AMINO-4-METHYLCOUMARIN

Z-LLE-AMC

Z-ILE-AMC

N-[(Benzyloxy)carbonyl]-L-leucyl-L-leucyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-α-glutamine

Z-LEU-LEU-GLU-MCA

Cbz-Leu-Leu-Glu-AMC,Z-LLE-AMC

L-α-Glutamine, N-[(phenylmethoxy)carbonyl]-L-leucyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-

Z-LEU-LEU-GLU-7-AMIDO-4-METHYLCOUMARIN

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