CAS 256224-02-9|2-AMINO-3'-O-(2-METHOXYETHYL)ADENOSINE

Introduction:Basic information about CAS 256224-02-9|2-AMINO-3'-O-(2-METHOXYETHYL)ADENOSINE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name2-AMINO-3'-O-(2-METHOXYETHYL)ADENOSINE
CAS Number256224-02-9Molecular Weight340.34
Density/Boiling Point/
Molecular FormulaC13H20N6O5Melting Point/
MSDS/Flash Point/

Names

Name(2R,3R,4S,5R)-2-(2,6-diaminopurin-9-yl)-5-(hydroxymethyl)-4-(2-methoxyethoxy)oxolan-3-ol

2-AMINO-3'-O-(2-METHOXYETHYL)ADENOSINE BiologicalActivity

Description3’-O-(2-Methoxyethyl)-2-aminoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

[2]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

Chemical & Physical Properties

Molecular FormulaC13H20N6O5
Molecular Weight340.34
Exact Mass340.15000
PSA163.79000
InChIKeyCUAPZJHEUMOFCW-WOUKDFQISA-N
SMILESCOCCOC1C(CO)OC(n2cnc3c(N)nc(N)nc32)C1O
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