CAS 31712-49-9|Hesperetin 7-O-glucoside

Introduction：Basic information about CAS 31712-49-9|Hesperetin 7-O-glucoside, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Hesperetin 7-O-glucoside BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Hesperetin 7-O-glucoside
CAS Number	31712-49-9	Molecular Weight	464.419
Density	1.6±0.1 g/cm3	Boiling Point	807.1±65.0 °C at 760 mmHg
Molecular Formula	C₂₂H₂₄O₁₁	Melting Point	/
MSDS	/	Flash Point	282.0±27.8 °C

Names

Name	hesperetin 7-O-β-D-glucoside
Synonym	More Synonyms

Hesperetin 7-O-glucoside BiologicalActivity

Description	Hesperetin 7-O-glucoside is produced by the enzymatic conversion of Hesperidin. Hesperetin 7-O-glucoside is a potent human HMG-CoA reductase inhibitor and also effectively inhibits the growth of Helicobacter pylori. Antihypertensive effect[1][2].
Related Catalog	Signaling Pathways >>Metabolic Enzyme/Protease >>HMG-CoA Reductase (HMGCR)Research Areas >>InfectionResearch Areas >>Metabolic DiseaseSignaling Pathways >>Anti-infection >>Bacterial
References	[1]. Young-Su Lee, et al. Enzymatic Bioconversion of Citrus Hesperidin by Aspergillus Sojae Naringinase: Enhanced Solubility of hesperetin-7-O-glucoside With in Vitro Inhibition of Human Intestinal Maltase, HMG-CoA Reductase, and Growth of Helicobacter Pylori. Food Chem. 2012 Dec 15;135(4):2253-9. [2]. Lucas Actis-Goretta, et al. Gastrointestinal Absorption and Metabolism of hesperetin-7-O-rutinoside and hesperetin-7-O-glucoside in Healthy Humans. Mol Nutr Food Res. 2015 Sep;59(9):1651-62.

Description

Hesperetin 7-O-glucoside is produced by the enzymatic conversion of Hesperidin. Hesperetin 7-O-glucoside is a potent human HMG-CoA reductase inhibitor and also effectively inhibits the growth of Helicobacter pylori. Antihypertensive effect[1][2].

Related Catalog

Signaling Pathways >>Metabolic Enzyme/Protease >>HMG-CoA Reductase (HMGCR)Research Areas >>InfectionResearch Areas >>Metabolic DiseaseSignaling Pathways >>Anti-infection >>Bacterial

References

[1]. Young-Su Lee, et al. Enzymatic Bioconversion of Citrus Hesperidin by Aspergillus Sojae Naringinase: Enhanced Solubility of hesperetin-7-O-glucoside With in Vitro Inhibition of Human Intestinal Maltase, HMG-CoA Reductase, and Growth of Helicobacter Pylori. Food Chem. 2012 Dec 15;135(4):2253-9.

[2]. Lucas Actis-Goretta, et al. Gastrointestinal Absorption and Metabolism of hesperetin-7-O-rutinoside and hesperetin-7-O-glucoside in Healthy Humans. Mol Nutr Food Res. 2015 Sep;59(9):1651-62.

Chemical & Physical Properties

Density	1.6±0.1 g/cm3
Boiling Point	807.1±65.0 °C at 760 mmHg
Molecular Formula	C₂₂H₂₄O₁₁
Molecular Weight	464.419
Flash Point	282.0±27.8 °C
Exact Mass	464.131866
PSA	175.37000
LogP	0.52
Vapour Pressure	0.0±3.0 mmHg at 25°C
Index of Refraction	1.672
InChIKey	ADSYMQORONDIDD-ZJHVPRRPSA-N
SMILES	COc1ccc(C2CC(=O)c3c(O)cc(OC4OC(CO)C(O)C(O)C4O)cc3O2)cc1O

Safety Information

Hazard Codes	Xi

Synonyms

hesperetin 7-O-beta-D-glucoside

4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (S)-

5,7,3'-trihydroxy-4'-methoxyl flavanone 7-O-glucoside

4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (2S)-

Hesperetin 7-O-glucoside

HESPERETIN

(2S)-5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl β-D-glucopyranoside

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