Introduction：Basic information about CAS 25526-94-7|3'-Chloro-3'-deoxythymidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 3'-Chloro-3'-deoxythymidine |
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| CAS Number | 25526-94-7 | Molecular Weight | 260.67 |
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| Density | 1.5±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C10H13ClN2O4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 3'-Desoxy-3'-chlor-thymidin |
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| Synonym | More Synonyms |
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3'-Chloro-3'-deoxythymidine BiologicalActivity
| Description | 3′-Chloro-3′-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
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| Molecular Formula | C10H13ClN2O4 |
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| Molecular Weight | 260.67 |
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| Exact Mass | 260.056396 |
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| PSA | 84.32000 |
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| LogP | -0.63 |
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| Index of Refraction | 1.598 |
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| InChIKey | KQVJDKGDGLWBQT-XLPZGREQSA-N |
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| SMILES | Cc1cn(C2CC(Cl)C(CO)O2)c(=O)[nH]c1=O |
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Safety Information
| RIDADR | NONH for all modes of transport |
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Synonyms
| 3'-Chloro-3'-deoxythymidine (Zidovudine Related Compound B) |
| Zidovudine Related Compound B |
| 3'-Chloro-3'-deoxythymidine |
| Thymidine, 3'-chloro-3'-deoxy- |
