CAS 13276-43-2|2-chloroinosine

Introduction:Basic information about CAS 13276-43-2|2-chloroinosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name2-chloroinosine
CAS Number13276-43-2Molecular Weight302.67
Density2.194 g/cm3Boiling Point/
Molecular FormulaC10H11ClN4O5Melting Point141-143ºC (dec.)
MSDS/Flash Point/

Names

Name2-chloro-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
SynonymMore Synonyms

2-chloroinosine BiologicalActivity

Description2-Chloroinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

Density2.194 g/cm3
Melting Point141-143ºC (dec.)
Molecular FormulaC10H11ClN4O5
Molecular Weight302.67
Exact Mass302.04200
PSA133.49000
Storage condition-20°C Freezer

Synonyms

2-Chloroinosine
2-Chlor-inosin
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