CAS 136724-73-7|Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2
| Common Name | Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 | ||
|---|---|---|---|
| CAS Number | 136724-73-7 | Molecular Weight | 724.73000 |
| Density | / | Boiling Point | / |
| Molecular Formula | C36H29N7O4Ru | Melting Point | / |
| MSDS | USA | Flash Point | / |
Names
| Name | bis-(bipyridin)-4'-methyl-4-carboxybipy. |
|---|---|
| Synonym | More Synonyms |
Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 BiologicalActivity
| Description | Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 is a potent ruthenium-based dye. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can bu used as an effective quencher of quantum dots (QDs) fluorescence and the capture probe of virus antigen EV71. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can be used sensitive electrogenerated chemiluminescence (ECL) labels for detection of matrix metalloproteinases (MMPs)[1][2][3]. |
|---|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
| In Vitro | Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can be used as a label to measure the hydrodynamic radii of intravitreal anti-VEGF drugs[2]. |
| References | [1]. Chen L, et al. Dual-color fluorescence and homogeneous immunoassay for the determination of human enterovirus 71. Anal Chem. 2011 Oct 1;83(19):7316-22. [2]. Hirvonen LM, et al. Hydrodynamic Radii of Ranibizumab, Aflibercept and Bevacizumab Measured by Time-Resolved Phosphorescence Anisotropy. Pharm Res. 2016 Aug;33(8):2025-32. [3]. HongfangGao, et al. Highly selective electrogenerated chemiluminescence biosensor for simultaneous detection of matrix metalloproteinase-2 and matrix metalloproteinase-7 in cell secretions. Sensors and Actuators B: Chemical, December 2017, 69-76. |
Chemical & Physical Properties
| Molecular Formula | C36H29N7O4Ru |
|---|---|
| Molecular Weight | 724.73000 |
| Exact Mass | 725.13200 |
| PSA | 141.02000 |
| LogP | 5.89790 |
| InChIKey | UQJZJWDQEYXDCR-UHFFFAOYSA-N |
| SMILES | Cc1ccnc(-c2cc(C(=O)ON3C(=O)CCC3=O)ccn2)c1.F[P-](F)(F)(F)(F)F.F[P-](F)(F)(F)(F)F.[Ru+2].c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1 |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles2
More Articles| pH-Dependent Excited-State Dynamics of [Ru(bpy)(3)](2+)-Modified Amino Acids: Effects of an Amide Linkage and Remote Functional Groups. Inorg. Chem. 38 , 2030, (1999) The pH-dependent photophysical properties of a series of polypyridyl ruthenium-substituted amino acids were investigated by steady-state and time-resolved luminescence spectroscopy. [H(3)N-DAPA(Rub(2)... | |
| Synthesis of redox derivatives of lysine and related peptides containing phenothiazine or tris(2,2'-bipyridine)ruthenium(II). Int. J. Pept. Protein Res. 38 , 114, (1991) Boc-L-Lysine derivatives and lysine-containing peptides bearing the electron donor 10H-phenothiazine (PTZ) or the redox chromophore tris(2,2'-bipyridine)ruthenium(II) dication ([Rub3]2+, where b is 2,... |
Synonyms
| bis-(Bipyridin)-4'-methyl-4-carboxybipy-Ru N-succinimidyl ester.PF6 |
| ru(bpy)2(mcbpy-o-su-ester)(pf6)2 |
| bis(2,2'-bipyridine)-4'-methyl-4-carboxybipyridine-ruthenium n-succinimidyl ester-bis(hexafluorophosphate) |
