CAS 6381-92-6|Disodium edetate dihydrate
| Common Name | Disodium edetate dihydrate | ||
|---|---|---|---|
| CAS Number | 6381-92-6 | Molecular Weight | 372.237 |
| Density | 1.01 g/mL at 25 °C | Boiling Point | >100 °C |
| Molecular Formula | C10H18N2Na2O10 | Melting Point | 250 °C (dec.)(lit.) |
| MSDS | ChineseUSA | Flash Point | 325.2ºC |
| Symbol | GHS07, GHS08 | Signal Word | Warning |
Names
| Name | EDTA disodium salt dihydrate |
|---|---|
| Synonym | More Synonyms |
Disodium edetate dihydrate BiologicalActivity
| Description | Ethylenediaminetetraacetic acid (EDTA) disodium dihydrate is a chelating agent used as a protease inhibitor and metal ion scavenger. Ethylenediaminetetraacetic acid disodium dihydrate is used extensively during protein purification. Ethylenediaminetetraacetic acid disodium dihydrate has been shown to be a noneffective molecule on cellulase activity. Ethylenediaminetetraacetic acid disodium dihydrate binds to metals including calcium and facilitates their excretion[1][2]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
| References | [1]. Ibad A, et al. Chelation therapy in the treatment of cardiovascular diseases. J Clin Lipidol. 2016;10(1):58-62. [2]. Chumanov RS, et al. Artifact-inducing enrichment of ethylenediaminetetraacetic acid and ethyleneglycoltetraacetic acid on anion exchange resins. Anal Biochem. 2011;412(1):34-39. |
Chemical & Physical Properties
| Density | 1.01 g/mL at 25 °C |
|---|---|
| Boiling Point | >100 °C |
| Melting Point | 250 °C (dec.)(lit.) |
| Molecular Formula | C10H18N2Na2O10 |
| Molecular Weight | 372.237 |
| Flash Point | 325.2ºC |
| Exact Mass | 372.075684 |
| PSA | 179.80000 |
| Index of Refraction | n20/D 1.363 |
| InChIKey | OVBJJZOQPCKUOR-UHFFFAOYSA-N |
| SMILES | O.O.O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O.[Na+].[Na+] |
| Storage condition | 2-8°C |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Water Solubility | soluble |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATAMUTATION DATA - TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 200 mg/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 163,63,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7050 No. of Facilities: 1244 (estimated) No. of Industries: 13 No. of Occupations: 20 No. of Employees: 12572 (estimated) No. of Female Employees: 8163 (estimated)
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 200 mg/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 163,63,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7050 No. of Facilities: 1244 (estimated) No. of Industries: 13 No. of Occupations: 20 No. of Employees: 12572 (estimated) No. of Female Employees: 8163 (estimated)
Safety Information
| Symbol | GHS07, GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H332-H373 |
| Precautionary Statements | P260 |
| Target Organs | Respiratory Tract |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/38 |
| Safety Phrases | S26-S61-S37/39-S36/37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | AH4025000 |
| HS Code | 29224995 |
Customs
| HS Code | 2922509090 |
|---|---|
| Summary | 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| DISODIUM EDTA DIHYDRATE |
| Edetate disodium dihydrate |
| Ethylenediaminetetraacetic acid disodium salt dihydrate |
| Sodium 2,2'-{1,2-ethanediylbis[(carboxymethyl)imino]}diacetate hydrate (2:1:2) |
| edta |
| EDTA disodium salt dihydrate |
| Sodium 2,2'-{ethane-1,2-diylbis[(carboxymethyl)imino]}diacetate hydrate (2:1:2) (non-preferred name) |
| EDTA disodium dihydrate |
| EINECS 205-358-3 |
| Disodium Dihydrogen Ethylenediaminetetraacetate Dihydrate |
| MFCD00003541 |
| Disodium edetate dihydrate |
| EDTA-2Na |
