CAS 139755-85-4|Hydroxyhomo Sildenafil

Introduction:Basic information about CAS 139755-85-4|Hydroxyhomo Sildenafil, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameHydroxyhomo Sildenafil
CAS Number139755-85-4Molecular Weight504.60200
Density1.42g/cm3Boiling Point730.6ºC at 760 mmHg
Molecular FormulaC23H32N6O5SMelting Point183-185 °C
MSDS/Flash Point395.7ºC

Names

Name5-[2-ethoxy-5-[4-(2-hydroxyethyl)piperazin-1-yl]sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one
SynonymMore Synonyms

Hydroxyhomo Sildenafil BiologicalActivity

DescriptionLodenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor for the treatment of erectile dysfunction (ED), with less oral bioavailability than Lodenafil carbonate[1].
Related CatalogResearch Areas >>EndocrinologySignaling Pathways >>Metabolic Enzyme/Protease >>Phosphodiesterase (PDE)
Target

PDE5

References

[1]. Toque HA, et al. Pharmacological characterization of a novel phosphodiesterase type 5 (PDE5) inhibitor lodenafil carbonate on human and rabbit corpus cavernosum. Eur J Pharmacol. 2008 Sep 4;591(1-3):189-95.

Chemical & Physical Properties

Density1.42g/cm3
Boiling Point730.6ºC at 760 mmHg
Melting Point183-185 °C
Molecular FormulaC23H32N6O5S
Molecular Weight504.60200
Flash Point395.7ºC
Exact Mass504.21500
PSA142.03000
LogP1.93000
Vapour Pressure2.08E-22mmHg at 25°C
Index of Refraction1.667

Safety Information

Hazard CodesXi

Synonyms

hydroxyhomosildenafil
Hydroxyhomo Sildenafil
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