Introduction：Basic information about CAS 16344-26-6|DHODH-IN-17, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | DHODH-IN-17 |
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| CAS Number | 16344-26-6 | Molecular Weight | 248.67 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C12H9ClN2O2 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 2-(4-chloroanilino)pyridine-3-carboxylic acid |
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| Synonym | More Synonyms |
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DHODH-IN-17 BiologicalActivity
| Description | DHODH-IN-17, a 2-anilino nicotinic acid, is a human DHODH inhibitor (IC50=0.40 μM). DHODH-IN-17 can be used for theresearch of acute myeloid leukemia (AML)[1]. |
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| Related Catalog | Research Areas >>Cancer |
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| Target | IC50: 0.4 μM (DHODH)[1] |
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| In Vitro | DHODH-IN-17, a 2-anilino nicotinic acid, is a human DHODH inhibitor with an IC50 value of 0.40 μM[1]. |
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| References | [1]. Lewis TA, et al. Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia. ACS Med Chem Lett. 2016;7(12):1112-1117. |
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Chemical & Physical Properties
| Molecular Formula | C12H9ClN2O2 |
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| Molecular Weight | 248.67 |
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| Exact Mass | 248.03500 |
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| PSA | 62.22000 |
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| LogP | 3.24980 |
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| InChIKey | YEXIXVLEDGNAKM-UHFFFAOYSA-N |
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| SMILES | O=C(O)c1cccnc1Nc1ccc(Cl)cc1 |
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Synonyms
| 2-[(4-chlorophenyl)amino]-3-pyridinecarboxylic acid |
| HMS2655G09 |
| 2-(4-chloro-anilino)-nicotinic acid |
| 2-(4-Chloro-phenylamino)-nicotinic acid |
| 2-(p-Chloranilino)-nicotinsaeure |
| 2-[(4-chlorophenyl)amino]pyridine-3-carboxylic acid |
