CAS 3934-84-7|3,4-Dihydroxy-5-methoxybenzoic acid

Introduction：Basic information about CAS 3934-84-7|3,4-Dihydroxy-5-methoxybenzoic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 3,4-Dihydroxy-5-methoxybenzoic acid BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	3,4-Dihydroxy-5-methoxybenzoic acid
CAS Number	3934-84-7	Molecular Weight	184.146
Density	1.5±0.1 g/cm3	Boiling Point	433.7±45.0 °C at 760 mmHg
Molecular Formula	C₈H₈O₅	Melting Point	220℃
MSDS	USA	Flash Point	183.6±22.2 °C

Names

Name	3-O-methylgallic acid
Synonym	More Synonyms

3,4-Dihydroxy-5-methoxybenzoic acid BiologicalActivity

Description	3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) is an anthocyanin metabolite and has potent antioxidant capacity. 3-O-methylgallic acid inhibits Caco-2 cell proliferation with an IC50 value of 24.1 μM. 3-O-methylgallic acid also induces cell apoptosis and has anti-cancer effects[1][2].
Related Catalog	Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cancer
References	[1]. Forester SC, et al. Gut metabolites of anthocyanins, gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde, inhibit cell proliferation of Caco-2 cells. J Agric Food Chem. 2010 May 12;58(9):5320-7. [2]. Forester SC, The anthocyanin metabolites gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde decrease human colon cancer cell viability by regulating pro-oncogenic signals. Mol Carcinog. 2014 Jun;53(6):432-9.

Description

3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) is an anthocyanin metabolite and has potent antioxidant capacity. 3-O-methylgallic acid inhibits Caco-2 cell proliferation with an IC50 value of 24.1 μM. 3-O-methylgallic acid also induces cell apoptosis and has anti-cancer effects[1][2].

Related Catalog

Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cancer

References

[1]. Forester SC, et al. Gut metabolites of anthocyanins, gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde, inhibit cell proliferation of Caco-2 cells. J Agric Food Chem. 2010 May 12;58(9):5320-7.

[2]. Forester SC, The anthocyanin metabolites gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde decrease human colon cancer cell viability by regulating pro-oncogenic signals. Mol Carcinog. 2014 Jun;53(6):432-9.

Chemical & Physical Properties

Density	1.5±0.1 g/cm3
Boiling Point	433.7±45.0 °C at 760 mmHg
Melting Point	220℃
Molecular Formula	C₈H₈O₅
Molecular Weight	184.146
Flash Point	183.6±22.2 °C
Exact Mass	184.037170
PSA	86.99000
LogP	1.19
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.629
InChIKey	KWCCUYSXAYTNKA-UHFFFAOYSA-N
SMILES	COc1cc(C(=O)O)cc(O)c1O

Safety Information

Hazard Codes	Xi
Risk Phrases	36/37/38
Safety Phrases	26-36/37/39
HS Code	2918990090

Customs

HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synonyms

3,4-Dihydroxy-5-methoxybenzoic acid

MFCD00016518

EINECS 223-512-8

Benzoic acid, 3,4-dihydroxy-5-methoxy-

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