Introduction：Basic information about CAS 250694-07-6|Teglicar, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Teglicar |
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| CAS Number | 250694-07-6 | Molecular Weight | 399.61100 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C22H45N3O3 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Teglicar |
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| Synonym | More Synonyms |
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Teglicar BiologicalActivity
| Description | Teglicar is a selective and reversible inhibitor of liver isoform of carnitine palmitoyl-transferase 1 (L-CPT1). Teglicar reduces ketogenesis and glucose production, decreases gluconeogenesis and improves glucose homeostasis. Teglicar has a potential antihyperglycemic propert[1]. |
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| Related Catalog | Research Areas >>Metabolic Disease |
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| Target | IC50: L-CPT1[1] |
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| References | [1]. Conti R, et al. Selective reversible inhibition of liver carnitine palmitoyl-transferase 1 by teglicar reduces gluconeogenesis and improves glucose homeostasis. Diabetes. 2011 Feb;60(2):644-51. |
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Chemical & Physical Properties
| Molecular Formula | C22H45N3O3 |
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| Molecular Weight | 399.61100 |
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| Exact Mass | 399.34600 |
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| PSA | 81.26000 |
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| LogP | 3.98330 |
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| InChIKey | BMZYTDRMCBZVNH-HXUWFJFHSA-N |
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| SMILES | CCCCCCCCCCCCCCN=C([O-])NC(CC(=O)O)C[N+](C)(C)C |
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Synonyms
| (R)-4-Trimethylammonio-3-[(tetradecylcarbamoyl)amino]butyrate |
| ST 1326 |
| 3-(TETRADECYLCARBAMOYLAMINO)-4-TRIMETHYLAMMONIO-BUTANOATE |
| 1-Propanaminium,3-carboxy-N,N,N-trimethyl-2-[[(tetradecylamino)carbonyl]amino]-,inner salt,(2R) |
| R-4-trimethylammonium-3-(tetradecylcarbamoyl)-aminobutyrate |
| 3-(tetradecylcarbamoylamino)-4-(trimethylazaniumyl)butanoate |
| 4-trimethylammonium-(R)-3-(tetradecylcarbamoyl)-amino butyrate |
