CAS 2579-20-6|1,3-Cyclohexanediyldimethanamine

Introduction：Basic information about CAS 2579-20-6|1,3-Cyclohexanediyldimethanamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles3
7. Synonyms

Common Name	1,3-Cyclohexanediyldimethanamine
CAS Number	2579-20-6	Molecular Weight	142.242
Density	0.9±0.1 g/cm3	Boiling Point	219.9±8.0 °C at 760 mmHg
Molecular Formula	C₈H₁₈N₂	Melting Point	-70 °C
MSDS	ChineseUSA	Flash Point	106.1±0.0 °C
Symbol	GHS05, GHS07	Signal Word	Danger

Names

Name	[3-(aminomethyl)cyclohexyl]methanamine
Synonym	More Synonyms

Chemical & Physical Properties

Density	0.9±0.1 g/cm3
Boiling Point	219.9±8.0 °C at 760 mmHg
Melting Point	-70 °C
Molecular Formula	C₈H₁₈N₂
Molecular Weight	142.242
Flash Point	106.1±0.0 °C
Exact Mass	142.147003
PSA	52.04000
LogP	0.47
Vapour Pressure	0.1±0.4 mmHg at 25°C
Index of Refraction	1.478
Storage condition	2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GU7000000

CHEMICAL NAME :: Cyclohexane, 1,3-bis(aminomethyl)-

CAS REGISTRY NUMBER :: 2579-20-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C8-H18-N2

MOLECULAR WEIGHT :: 142.28

WISWESSER LINE NOTATION :: L6TJ A1Z C1Z

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 880 mg/kg

TOXIC EFFECTS :: Gastrointestinal - other changes

REFERENCE :: HURC** Huntingdon Research Center Reports. (Box 527, Brooklandville, MD 21022) Volume(issue)/page/year: -,-,1973

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971

Safety Information

Symbol	GHS05, GHS07
Signal Word	Danger
Hazard Statements	H302 + H312-H314-H412
Precautionary Statements	P273-P280-P305 + P351 + P338-P310
Personal Protective Equipment	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	C
Risk Phrases	R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . R34:Causes burns. R22:Harmful if swallowed.
Safety Phrases	S26-S27-S28-S36/37/39-S45-S25
RIDADR	UN 2735 8/PG 2
WGK Germany	3
RTECS	GU7000000
Packaging Group	I
Hazard Class	8
HS Code	2921300090

Customs

HS Code	2921300090
Summary	2921300090 other cyclanic, cyclenic or cyclotherpenic mono- or polyamines, and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles3

Retrograde transport of protein toxins under conditions of COPI dysfunction.

Biochim. Biophys. Acta 1589(2) , 124-39, (2002)

Retrograde transport dependent on coat protein I (COPI) was impaired using two different approaches and the effects on the retrograde transport of protein toxins were investigated. One approach was to...

Use of aminoglycoside antibiotics and related compounds to study ADP-ribosylation factor (ARF)/coatomer function in Golgi traffic.

Meth. Enzymol. 329 , 372-9, (2001)

Inhibition of secretion by 1,3-Cyclohexanebis(methylamine), a dibasic compound that interferes with coatomer function.

Mol. Biol. Cell 10(4) , 921-33, (1999)

We noted previously that certain aminoglycoside antibiotics inhibit the binding of coatomer to Golgi membranes in vitro. The inhibition is mediated in part by two primary amino groups present at the 1...

Synonyms

1,3-Di(aminomethyl)cyclohexane

L6TJ A1Z C1Z

1,3-Cyclohexanebis(methylamine)

Kodak silver halide solvent HS-103

EINECS 219-941-5

1,3-Bis(aminomethyl)cyclohexane

1,3-Cyclohexanedimethanamine

1,3-Cyclohexanediyldimethanamine

Hexahydro-m-xylylenediamine

MFCD00001522

Cyclohexane-1,3-diyldimethanamine

trans 1,3-bis-aminomethylcyclohexane

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