Introduction：Basic information about CAS 160415-07-6|SCH 50911 hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | SCH 50911 hydrochloride |
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| CAS Number | 160415-07-6 | Molecular Weight | 173.21000 |
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| Density | 1.055 g/cm3 | Boiling Point | 305.5ºC at 760 mmHg |
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| Molecular Formula | C8H16ClNO3 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | 138.6ºC |
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| Symbol |
GHS07 | Signal Word | Warning |
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Names
| Name | (2s)-(+)-5,5-dimethyl-2-morpholineacetic acid |
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| Synonym | More Synonyms |
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SCH 50911 hydrochloride BiologicalActivity
| Description | SCH 50911 hydrochloride, (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid, a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, binds to GABA(B) receptor with IC50 of 1.1 μM. SCH 50911 hydrochloride antagonizes GABA(B) autoreceptors, increasing the electrically-stimulated 3H overflow with an IC50 of 3 μM. |
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| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>GABA ReceptorResearch Areas >>Neurological DiseaseSignaling Pathways >>Neuronal Signaling >>GABA Receptor |
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| Target | GABA(B):1.1 μM (IC50) |
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| References | [1]. Ong J, et al. The morpholino-acetic acid analogue Sch 50911 is a selective GABA(B) receptor antagonist in rat neocortical slices. Eur J Pharmacol. 1998 Nov 27;362(1):35-41. |
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Chemical & Physical Properties
| Density | 1.055 g/cm3 |
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| Boiling Point | 305.5ºC at 760 mmHg |
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| Molecular Formula | C8H16ClNO3 |
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| Molecular Weight | 173.21000 |
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| Flash Point | 138.6ºC |
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| Exact Mass | 173.10500 |
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| PSA | 58.56000 |
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| LogP | 0.55690 |
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| Vapour Pressure | 0.000187mmHg at 25°C |
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| Index of Refraction | 1.444 |
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| InChIKey | QYYBBASPKHNBKA-RGMNGODLSA-N |
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| SMILES | CC1(C)COC(CC(=O)O)CN1.Cl |
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Safety Information
| Symbol |
GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H317 |
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| Precautionary Statements | P280 |
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| Hazard Codes | Xi |
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| RIDADR | NONH for all modes of transport |
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| HS Code | 2934999090 |
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Customs
| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| (+)-(2S)-5,5-Dimethyl-2-morpholineacetic acid hydrochloride |
