Introduction：Basic information about CAS 13227-01-5|4-Methylphenyl glycine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-Methylphenyl glycine |
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| CAS Number | 13227-01-5 | Molecular Weight | 165.189 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 271.0±23.0 °C at 760 mmHg |
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| Molecular Formula | C9H11NO2 | Melting Point | 256-257ºC |
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| MSDS | / | Flash Point | 131.7±20.1 °C |
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Names
| Name | 2-amino-2-(4-methylphenyl)acetic acid |
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| Synonym | More Synonyms |
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4-Methylphenyl glycine BiologicalActivity
| Description | 2-Amino-2-(p-tolyl)acetic acid is used for optimizing azide skeleton, and is the intermediate in the synthesis of 1,3, 4-thiadiazole compounds. 1,3,4-thiadiazole compounds exhibit potential anti-cancer activity, and inhibit glutaminase (GLSI)[1][2]. |
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| Related Catalog | Research Areas >>Cancer |
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| References | [1]. Kalie A M, et al. Cytosolic Delivery of Proteins by Bioreversible Esterification. JAmChem. 2017. 139(41):14396–14398. [2]. Finlay MRV, et al. Preparation of 1,3,4-thiadiazole compounds and their use in treating cancer: World Intellectual Property Organization, WO2017093301[P]. 2017-06-08. |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 271.0±23.0 °C at 760 mmHg |
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| Melting Point | 256-257ºC |
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| Molecular Formula | C9H11NO2 |
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| Molecular Weight | 165.189 |
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| Flash Point | 131.7±20.1 °C |
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| Exact Mass | 165.078979 |
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| PSA | 63.32000 |
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| LogP | 1.27 |
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| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
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| Index of Refraction | 1.538 |
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| InChIKey | RZRRCPHBUKHOEY-UHFFFAOYSA-N |
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| SMILES | Cc1ccc(C(N)C(=O)O)cc1 |
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Safety Information
| Hazard Codes | Xi |
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| HS Code | 2922499990 |
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Customs
| HS Code | 2922499990 |
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| Summary | HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0% |
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Synonyms
| MFCD00665357 |
| Glycine, 4-methylphenyl ester |
| 4-Methylphenyl glycinate |
| Benzeneacetic acid, α-amino-4-methyl- |
| 2-Amino-2-(4-methylphenyl)acetic acid |
| F2147-0646 |
| 2-Amino-2-(p-tolyl)acetic acid |
| Amino(4-methylphenyl)acetic acid |
| DL-4-Methylphenylglycine |
| aminomethylphenylaceticacid |
| 4-Methylphenyl glycine |
| Amino-p-tolyl-acetic acid |
