Introduction：Basic information about CAS 13410-86-1|Aconiazide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Aconiazide |
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| CAS Number | 13410-86-1 | Molecular Weight | 299.28100 |
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| Density | 1.3g/cm3 | Boiling Point | / |
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| Molecular Formula | C15H13N3O4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 2-[2-[(E)-(pyridine-4-carbonylhydrazinylidene)methyl]phenoxy]acetic acid |
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| Synonym | More Synonyms |
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Aconiazide BiologicalActivity
| Description | Aconiazide (Isonicophen) is a orally active hydrazone derivative of isoniazid, and can be used for study of tuberculosis[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Others >>Others |
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| References | [1]. KENNETH L. DOOLEY, et al. Fourteen-Day , Repeat-Dose Toxicity Evaluation of Aconiazide _- Administered Orally to Male and Female Fischer 344 Rats. JOURNAL OF THE AMERICAN COLLEGE OF TOXICOLOGY Vdume 12, Number 4, 1993 |
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Chemical & Physical Properties
| Density | 1.3g/cm3 |
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| Molecular Formula | C15H13N3O4 |
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| Molecular Weight | 299.28100 |
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| Exact Mass | 299.09100 |
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| PSA | 100.88000 |
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| LogP | 1.69980 |
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| Index of Refraction | 1.61 |
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| InChIKey | MDFXJBQEWLCGHP-MFOYZWKCSA-N |
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| SMILES | O=C(O)COc1ccccc1C=NNC(=O)c1ccncc1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- US5638000
- CHEMICAL NAME :
- 4-Pyridinecarboxylic acid, ((2-(carboxymethoxy)phenyl)methylene)hydrazide
- CAS REGISTRY NUMBER :
- 13410-86-1
- BEILSTEIN REFERENCE NO. :
- 0300804
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C15-H13-N3-O4
- MOLECULAR WEIGHT :
- 299.31
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7 gm/kg/14D-I
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - structural change in nerve or sheath Liver - fatty liver degeneration Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 12,329,1993
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 36400 mg/kg/26W-I
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - structural change in nerve or sheath Blood - changes in erythrocyte (RBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 14,328,1995
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Safety Information
Customs
| HS Code | 2933399090 |
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| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| [2-(isonicotinoylhydrazono-methyl)-phenoxy]-acetic acid |
| Isonicophen |
| Aconiazid |
| Phenoxalid |
| ACONIAZIDE |
| [2-(Isonicotinoylhydrazono-methyl)-phenoxy]-essigsaeure |
