Introduction：Basic information about CAS 2517-04-6|Azetidine-2-carboxylic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Azetidine-2-carboxylic acid |
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| CAS Number | 2517-04-6 | Molecular Weight | 101.104 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 242.0±33.0 °C at 760 mmHg |
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| Molecular Formula | C4H7NO2 | Melting Point | 217°C (rough estimate) |
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| MSDS | / | Flash Point | 100.1±25.4 °C |
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Names
| Name | azetidine-2-carboxylic acid |
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| Synonym | More Synonyms |
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Azetidine-2-carboxylic acid BiologicalActivity
| Description | Azetidine-2-carboxylic acid is a non proteinogenic amino acid homologue of proline. Found in common beets. Azetidine-2-carboxylic acid can be misincorporated into proteins in place of proline in many species, including humans. Toxic and teratogenic agent[1][2]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>CancerNatural Products >>Others |
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| In Vitro | Azetidine-2-carboxylic acid (375-5oo μg per day) is incorporated into the collagen synthesized by chick embryo cartilage in vitro[3]. |
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| References | [1]. Rubenstein E, et al. Azetidine-2-carboxylic acid in the food chain. Phytochemistry. 2009 Jan;70(1):100-4. [2]. Rubenstein E, et al. Misincorporation of the proline analog azetidine-2-carboxylic acid in the pathogenesis of multiple sclerosis: a hypothesis. J Neuropathol Exp Neurol. 2008 Nov;67(11):1035-40. [3]. Lane JM, et al. Effect of the proline analogue azetidine-2-carboxylic acid on collagen synthesis in vivo. I. Arrest of collagen accumulation in growing chick embryos. Biochim Biophys Acta. 1971 Jun 29;236(3):517-27. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 242.0±33.0 °C at 760 mmHg |
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| Melting Point | 217°C (rough estimate) |
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| Molecular Formula | C4H7NO2 |
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| Molecular Weight | 101.104 |
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| Flash Point | 100.1±25.4 °C |
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| Exact Mass | 101.047676 |
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| PSA | 49.33000 |
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| LogP | -0.83 |
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| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
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| Index of Refraction | 1.499 |
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| InChIKey | IADUEWIQBXOCDZ-UHFFFAOYSA-N |
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| SMILES | O=C(O)C1CCN1 |
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Safety Information
| Hazard Codes | Xi |
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| HS Code | 2933990090 |
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Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| Azetidine-2-carboxylic acid |
| (±)-2-Azetidinecarboxylic Acid |
| UNII:775261TI36 |
| 2-Azetidinecarboxylic acid |
| 2-azetidine-carboxylic acid |
| 2-carboxyazetidine |
| azetidinecarboxylic acid |
| azethidine-2-carboxylic acid |
| 1-AZETIDINESULFONAMIDE |
| azetidine-1-sulphonamide |
| EINECS 219-740-2 |
