CAS 25496-72-4|Glyceryl monooleate

Introduction:Basic information about CAS 25496-72-4|Glyceryl monooleate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameGlyceryl monooleate
CAS Number25496-72-4Molecular Weight356.540
Density1.0±0.1 g/cm3Boiling Point483.3±35.0 °C at 760 mmHg
Molecular FormulaC21H40O4Melting Point36 - 40ºC
MSDS/Flash Point155.4±19.4 °C

Names

NameGlycerol mono-oleate
SynonymMore Synonyms

Glyceryl monooleate BiologicalActivity

DescriptionGlycerol Monoleate is a nontoxic, biodegradable and biocompatible, lipophilic glycerol fatty acid ester. Glycerol monooleate has hemolytic properties. glycerol monooleate is used as an emulsifier and an absorption enhancer in combination with bile salts. Glycerol Monoleate can be used in drug delivery systems and siRNA delivery in Vitro[1][2].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
References

[1]. Milak S, et al. Glycerol monooleate liquid crystalline phases used in drug delivery systems. Int J Pharm. 2015 Jan 30;478(2):569-87.

[2]. Zhen G, et al. Glycerol monooleate-based nanocarriers for siRNA delivery in vitro. Mol Pharm. 2012 Sep 4;9(9):2450-7.

Chemical & Physical Properties

Density1.0±0.1 g/cm3
Boiling Point483.3±35.0 °C at 760 mmHg
Melting Point36 - 40ºC
Molecular FormulaC21H40O4
Molecular Weight356.540
Flash Point155.4±19.4 °C
Exact Mass356.292664
PSA66.76000
LogP6.71
Vapour Pressure0.0±2.8 mmHg at 25°C
Index of Refraction1.479
InChIKeyRZRNAYUHWVFMIP-MDZDMXLPSA-N
SMILESCCCCCCCCC=CCCCCCCCC(=O)OCC(O)CO
Storage condition−20°C
Water Solubilitychloroform: 50 mg/mL, clear, colorless

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RK1300000
CHEMICAL NAME :
Olein, mono-
CAS REGISTRY NUMBER :
25496-72-4
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C21-H40-O4
MOLECULAR WEIGHT :
356.61

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 5(5),391,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 5(5),391,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83110 No. of Facilities: 4016 (estimated) No. of Industries: 41 No. of Occupations: 51 No. of Employees: 74220 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83110 No. of Facilities: 9941 (estimated) No. of Industries: 81 No. of Occupations: 78 No. of Employees: 159120 (estimated) No. of Female Employees: 39063 (estimated)

Safety Information

RIDADRNONH for all modes of transport
WGK Germany1

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Synonyms

Glyceryl cis-9-octadecenoate
9-Octadecenoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (9Z)-
Oleic monoglyceride
9-Octadecenoic acid (9Z)-, monoester with 1,2,3-propanetriol
1-monooleoyl-rac-glycerol
1-(cis-9-Octadecenoyl)-rac-glycerol
1-Monooleoylglycerol
rac-Glycerol 1-monooleate
Glycerin 1-monooleate
glycerol monooleate
rac 1-Oleoyl Glycerol
4,5-Dihydroxypentyl (7Z)-7-hexadecenoate
Glycerin monooleate
Oleic acid glycerol monoester
1,3-Dihydroxypropan-2-yl (9Z)-octadec-9-enoate
Glycerine monooleate
1-O-Oleyl-rac-glycerol
1-oleoyl glycerol
1-OLEOYLGLYCEROL
OLEOYL GLYCEROL
GLYCEROL OLEATE
9-Octadecenoic acid, 2,3-dihydroxypropyl ester, (9Z)-
1,3-Dihydroxy-2-propanyl (9Z)-9-octadecenoate
MFCD00042735
2,3-Dihydroxypropyl (9Z)-9-octadecenoate
2,3-Dihydroxypropyl oleate
GLYCEROL MONO-OLEATE
MONO OLEIN
Glycerine oleate
1-GLYCERYL OLEATE
Glycerol Alpha-Monooleate
GLYCERYL MONOOLEATE
2,3-Dihydroxypropyl (9Z)-octadec-9-enoate
a-Monoolein
DL-ALPHA-MONOOLEIN
Monoolein 9 C18:1
Danisco MO 90
GLYCEROL MONO OLEATE
Monoolein (VAN)
2-hydroxy-1-(hydroxymethyl)ethyl (9Z)-octadec-9-enoate
1-Oleoyl-rac-glycerol
2-Oleoylglycerol
Glyceryl Monooleate (VAN)
RAC.-1-OLEOYL-GLYCEROL BIOCHEMICA
(9Z)-9-Octadecenoic Acid 2,3-Dihydroxypropyl Ester
dl-α-Monoolein
Glycerol α-monooleate
UNII:D3AEF6S35P
α-Monoolein
rac-1-Monooleoylglycerol
7-Hexadecenoic acid, 4,5-dihydroxypentyl ester, (7Z)-
9-Octadecenoic acid (9Z)-, ester with 1,2,3-propanetriol
Monoolein
1-Mono(cis-9-octacenoyl)glycerol
EINECS 247-038-6
Aldo HMO
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