Introduction：Basic information about CAS 651042-82-9|m-PEG7-thiol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | m-PEG7-thiol |
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| CAS Number | 651042-82-9 | Molecular Weight | 356.47500 |
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| Density | 1.065 | Boiling Point | / |
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| Molecular Formula | C15H32O7S | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | / |
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Names
| Name | 2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanethiol |
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| Synonym | More Synonyms |
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m-PEG7-thiol BiologicalActivity
| Description | m-PEG7-thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1] |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |
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Chemical & Physical Properties
| Density | 1.065 |
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| Molecular Formula | C15H32O7S |
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| Molecular Weight | 356.47500 |
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| Exact Mass | 356.18700 |
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| PSA | 103.41000 |
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| LogP | 0.66220 |
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| InChIKey | PVSKDHZQTUFAEZ-UHFFFAOYSA-N |
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| SMILES | COCCOCCOCCOCCOCCOCCOCCS |
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| Storage condition | -20°C |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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Articles1
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Synonyms
| O-(2-Mercaptoethyl)-O inverted exclamation marka-methyl-hexa(ethylene glycol) |
| AmbotzPEG1167 |
| mPEG thiol |
| 2,5,8,11,14,17,20-HEPTAOXADOCOSANE-22-THIOL |
| O-(2-Mercaptoethyl)-O'-methyl-hexa(ethylene glycol) |
