Introduction：Basic information about CAS 651042-83-0|m-PEG8-thiol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | m-PEG8-thiol |
|---|
| CAS Number | 651042-83-0 | Molecular Weight | 400.52800 |
|---|
| Density | 1.07 | Boiling Point | / |
|---|
| Molecular Formula | C17H36O8S | Melting Point | / |
|---|
| MSDS | / | Flash Point | / |
|---|
Names
| Name | 2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanethiol |
|---|
| Synonym | More Synonyms |
|---|
m-PEG8-thiol BiologicalActivity
| Description | m-PEG8-thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
|---|
| Target | PEGs |
|---|
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
|---|
| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
|---|
Chemical & Physical Properties
| Density | 1.07 |
|---|
| Molecular Formula | C17H36O8S |
|---|
| Molecular Weight | 400.52800 |
|---|
| Exact Mass | 400.21300 |
|---|
| PSA | 112.64000 |
|---|
| LogP | 0.67880 |
|---|
| InChIKey | LWTPDVASPXFETP-UHFFFAOYSA-N |
|---|
| SMILES | COCCOCCOCCOCCOCCOCCOCCOCCS |
|---|
| Storage condition | 2-8°C |
|---|
Synonyms
| 2,5,8,11,14,17,20,23-octaoxapentacosane-25-thiol |
