Introduction：Basic information about CAS 441771-60-4|m-PEG6-thiol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | m-PEG6-thiol |
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| CAS Number | 441771-60-4 | Molecular Weight | 312.42300 |
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| Density | 1.057 | Boiling Point | / |
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| Molecular Formula | C13H28O6S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanethiol |
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| Synonym | More Synonyms |
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m-PEG6-thiol BiologicalActivity
| Description | m-PEG6-thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.057 |
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| Molecular Formula | C13H28O6S |
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| Molecular Weight | 312.42300 |
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| Exact Mass | 312.16100 |
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| PSA | 94.18000 |
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| LogP | 0.64560 |
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| InChIKey | FCNSUDTWFXNQBG-UHFFFAOYSA-N |
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| SMILES | COCCOCCOCCOCCOCCOCCS |
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Safety Information
Synonyms
| 3,6,9,12,15,18-hexaoxanonadecane-1-thiol |
