Introduction：Basic information about CAS 136-70-9|Protokylol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Protokylol |
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| CAS Number | 136-70-9 | Molecular Weight | 331.36300 |
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| Density | 1.336g/cm3 | Boiling Point | 585ºC at 760 mmHg |
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| Molecular Formula | C18H21NO5 | Melting Point | / |
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| MSDS | / | Flash Point | 307.6ºC |
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Names
| Name | 4-[2-[1-(1,3-benzodioxol-5-yl)propan-2-ylamino]-1-hydroxyethyl]benzene-1,2-diol |
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| Synonym | More Synonyms |
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Protokylol BiologicalActivity
| Description | Protokylol (Caytine; JB-251) is a beta-adrenergic receptor agonist and TRPV1 agonist. Protokylol is used as a bronchodilator[1]. |
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| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>TRP ChannelResearch Areas >>Cardiovascular DiseaseSignaling Pathways >>GPCR/G Protein >>Adrenergic Receptor |
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| References | [1]. Corina Andrei, et al. In Silico Drug Repurposing Framework Predicts Repaglinide, Agomelatine and Protokylol as TRPV1 Modulators with Analgesic Activity. Pharmaceutics. 2022 Nov 22;14(12):2563. |
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Chemical & Physical Properties
| Density | 1.336g/cm3 |
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| Boiling Point | 585ºC at 760 mmHg |
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| Molecular Formula | C18H21NO5 |
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| Molecular Weight | 331.36300 |
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| Flash Point | 307.6ºC |
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| Exact Mass | 331.14200 |
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| PSA | 91.18000 |
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| LogP | 2.47160 |
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| Vapour Pressure | 1.57E-14mmHg at 25°C |
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| Index of Refraction | 1.638 |
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| InChIKey | LUMAEVHDZXIGEP-UHFFFAOYSA-N |
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| SMILES | CC(Cc1ccc2c(c1)OCO2)NCC(O)c1ccc(O)c(O)c1 |
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Synonyms
| EINECS 205-255-3 |
| JB 251 |
| protokylol |
| AN 1031 |
| Beres |
