Introduction：Basic information about CAS 1357072-61-7|c-Met inhibitor 1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | c-Met inhibitor 1 |
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| CAS Number | 1357072-61-7 | Molecular Weight | 362.412 |
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| Density | 1.6±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C17H14N8S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 3-(2-methylindazol-5-yl)sulfanyl-6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazine |
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| Synonym | More Synonyms |
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c-Met inhibitor 1 BiologicalActivity
| Description | c-Met inhibitor 1 is an inhibitor of the c-Met receptor signaling pathway useful for the treatment of cancer including gastric, glioblastoma, and pancreatic cancer. IC50 value:Target: c-MetMore details please refer to Patent WO 2012015677 A1. |
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| Related Catalog | Signaling Pathways >>Protein Tyrosine Kinase/RTK >>c-Met/HGFRResearch Areas >>Cancer |
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| References | [1]. PCT Int. Appl. (2012), WO 2012015677 A1 20120202. |
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Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
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| Molecular Formula | C17H14N8S |
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| Molecular Weight | 362.412 |
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| Exact Mass | 362.106201 |
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| PSA | 104.02000 |
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| LogP | 2.46 |
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| Index of Refraction | 1.838 |
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| InChIKey | JYXHZDNTBJUJNH-UHFFFAOYSA-N |
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| SMILES | Cn1cc(-c2ccc3nnc(Sc4ccc5nn(C)cc5c4)n3n2)cn1 |
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| Storage condition | 2-8℃ |
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Synonyms
| FD5012 |
| 3-[(2-Methyl-2H-indazol-5-yl)sulfanyl]-6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazine |
| 6-(1-METHYL-1H-PYRAZOL-4-YL)-3-((2-METHYL-2H-INDAZOL-5-YL)THIO)-[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE |
| 1,2,4-Triazolo[4,3-b]pyridazine, 3-[(2-methyl-2H-indazol-5-yl)thio]-6-(1-methyl-1H-pyrazol-4-yl)- |
| c-Met inhibitor 1 |
