Introduction：Basic information about CAS 31430-15-6|Flubendazole, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Flubendazole |
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| CAS Number | 31430-15-6 | Molecular Weight | 313.283 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C16H12FN3O3 | Melting Point | 290°C |
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| MSDS | ChineseUSA | Flash Point | / |
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Names
| Name | flubendazole |
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| Synonym | More Synonyms |
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Flubendazole BiologicalActivity
| Description | Flubendazole is a potent broad spectrum anthelmintic.Target: AntiparasiticFlubendazole is an anthelmintic. It is also available for human use to treat worm infections[1]. |
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| Related Catalog | Signaling Pathways >>Anti-infection >>ParasiteResearch Areas >>Infection |
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| References | [1]. http://www.patentstorm.us/patents/5824336/description.html |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Melting Point | 290°C |
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| Molecular Formula | C16H12FN3O3 |
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| Molecular Weight | 313.283 |
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| Exact Mass | 313.086273 |
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| PSA | 84.08000 |
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| LogP | 3.05 |
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| Index of Refraction | 1.685 |
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| InChIKey | CPEUVMUXAHMANV-UHFFFAOYSA-N |
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| SMILES | COC(=O)Nc1nc2ccc(C(=O)c3ccc(F)cc3)cc2[nH]1 |
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| Storage condition | -20°C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DD6497500
- CHEMICAL NAME :
- 2-Benzimidazolecarbamic acid, 5-(p-fluorobenzoyl)-, methyl ester
- CAS REGISTRY NUMBER :
- 31430-15-6
- LAST UPDATED :
- 199410
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C16-H12-F-N3-O3
- MOLECULAR WEIGHT :
- 313.31
- WISWESSER LINE NOTATION :
- T56 BM DNJ CMVO1 GVR DF
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2560 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2560 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 2560 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- >2560 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 320 mg/kg
- SEX/DURATION :
- female 8-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1280 mg/kg
- SEX/DURATION :
- female 8-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Specific Developmental Abnormalities - gastrointestinal system
MUTATION DATA - TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- REFERENCE :
- PCBRD2 Progress in Clinical and Biological Research. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1975- Volume(issue)/page/year: 340E,225,1990
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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| RTECS | DD6497500 |
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| HS Code | 2933990090 |
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Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Articles29
More Articles
| Flubendazole: a candidate macrofilaricide for lymphatic filariasis and onchocerciasis field programs. Expert Rev. Anti. Infect. Ther. 9(5) , 497-501, (2011)
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| Statistical analysis of the effects of polyethylene glycol concentration and molecular weight on the sedimentation and resuspendability behavior of model aqueous dispersions. Int. J. Pharm. 453(2) , 343-50, (2013) This work investigates the flocculation effect of polyethylene glycol (PEG) on typical aqueous dispersions, such as O/W emulsions and solid/liquid suspensions. Hereby, sunflower oil and flubendazole w... | |
| Transfer of flubendazole and tylosin from feed at cross-contamination levels to various poultry matrices. Poult. Sci. 91(9) , 2351-60, (2012) Residues of veterinary drugs and feed additives used extensively in animal husbandry are sometimes found in edible matrices. In this study, broilers received experimental feed, containing either flube... | |
Synonyms
| Biovermin |
| Methyl (5-(4-fluorobenzoyl)-1H-benzo[d]imidazol-2-yl)carbamate |
| Flubendazole |
| [5-(4-Fluorobenzoyl)benzimidazol-2-yl]carbamic Acid Methyl Ester |
| Flutelmium |
| EINECS 250-624-4 |
| FLUVERNAL |
| Flubendazol,Flumoxanal,Methyl [5-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate |
| [5-(4-Fluorobenzoyl)-1H-benzimidazol-2-yl]carbamic Acid Methyl Ester |
| Flubenol |
| fluvermal |
| Flumoxal |
| Carbamic acid, N-[5-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]-, methyl ester |
| Flumoxanal (Methyl [5-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate |
| methyl {6-[(4-fluorophenyl)carbonyl]-1H-benzimidazol-2-yl}carbamate |
| Flubenvet |
| Carbamicacid, [5-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]-methylester |
| Methyl {5-[(4-fluorophenyl)carbonyl]-1H-benzimidazol-2-yl}carbamate |
| MFCD00871999 |
| FLUMOXANAL |
| Methyl [5-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate |
| Methyl [5-(4-Fluorobenzoyl)benzimidazol-2-yl]carbamate |
| 5-(p-Fluorobenzoyl)-2-benzimidazolecarbamic Acid Methyl Ester |
| FLUMOXANE |
| Methyl-{5-[(4-fluorphenyl)carbonyl]-1H-benzimidazol-2-yl}carbamat |
| carbamic acid, [6-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]-, methyl ester |
