Introduction：Basic information about CAS 3440-28-6|Betamipron, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Betamipron |
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| CAS Number | 3440-28-6 | Molecular Weight | 193.19900 |
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| Density | 1.227 g/cm3 | Boiling Point | 469.2ºC at 760 mmHg |
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| Molecular Formula | C10H11NO3 | Melting Point | 132 °C |
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| MSDS | / | Flash Point | 237.6ºC |
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Names
| Name | 3-benzamidopropanoic acid |
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| Synonym | More Synonyms |
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Betamipron BiologicalActivity
| Description | Betamipron is a chemical compound which is used together with Panipenem to inhibit Panipenem uptake into the renal tubule and prevent nephrotoxicity. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Others |
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Chemical & Physical Properties
| Density | 1.227 g/cm3 |
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| Boiling Point | 469.2ºC at 760 mmHg |
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| Melting Point | 132 °C |
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| Molecular Formula | C10H11NO3 |
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| Molecular Weight | 193.19900 |
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| Flash Point | 237.6ºC |
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| Exact Mass | 193.07400 |
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| PSA | 66.40000 |
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| LogP | 1.28200 |
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| Index of Refraction | 1.557 |
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| InChIKey | CWXYHOHYCJXYFQ-UHFFFAOYSA-N |
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| SMILES | O=C(O)CCNC(=O)c1ccccc1 |
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| Storage condition | −20°C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- AY3272500
- CHEMICAL NAME :
- beta-Alanine, N-benzoyl-
- CAS REGISTRY NUMBER :
- 3440-28-6
- BEILSTEIN REFERENCE NO. :
- 2212769
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C10-H11-N-O3
- MOLECULAR WEIGHT :
- 193.22
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3496 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - cyanosis
- REFERENCE :
- NKRZAZ Chemotherapy (Tokyo). (Nippon Kagaku Ryoho Gakkai, 2-20-8 Kamiosaki, Shinagawa-Ku, Tokyo 141, Japan) V.1- 1953- Volume(issue)/page/year: 39(Suppl 3),140,1991 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 36 gm/kg/90D-C
- TOXIC EFFECTS :
- Blood - pigmented or nucleated red blood cells Blood - changes in erythrocyte (RBC) count Nutritional and Gross Metabolic - changes in sodium
- REFERENCE :
- NKRZAZ Chemotherapy (Tokyo). (Nippon Kagaku Ryoho Gakkai, 2-20-8 Kamiosaki, Shinagawa-Ku, Tokyo 141, Japan) V.1- 1953- Volume(issue)/page/year: 39(Suppl 3),157,1991
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Safety Information
| WGK Germany | 3 |
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| RTECS | AY3272500 |
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Articles25
More Articles
| Reaction of Pseudomonas fluorescens kynureninase with beta-benzoyl-L-alanine: detection of a new reaction intermediate and a change in rate-determining step. Biochemistry 43(11) , 3230-7, (2004) Beta-benzoyl-DL-alanine was synthesized from alpha-bromoacetophenone and diethyl acetamidomalonate. The racemic amino acid was resolved by carboxypeptidase A-catalyzed hydrolysis of the N-trifluoroace... | |
| Thermodynamic quantitative structure-activity relationship analysis for enzyme-ligand interactions in aqueous phosphate buffer and organic solvent. Bioorg. Med. Chem. 9(8) , 1951-5, (2001) Thermodynamic quantitative structure-activity relationships (QSAR) for chymotrypsin-ligand binding is developed, and the results are compared for the effects of organic solvent on the substrate specif... | |
| Nephroprotective effect of betamipron on a new carbapenem, DA-1131, in rabbits. Biopharm. Drug Dispos. 20(3) , 125-9, (1999) The nephroprotective effect of betamipron (200 mg/kg) was evaluated after intravenous administration of a high dose of DA-1131 (200 mg/kg) to rabbits. Extensive tubular necrosis was observed without b... | |
Synonyms
| 3-Benzamidopropanoic acid |
| MFCD00037293 |
| Benzoyl-β-alanine |
| 3-benzamidopropionic acid |
| Betamipron |
| 3-(Benzoylamino)propionic acid |
