CAS 25526-93-6|Alovudine

Introduction：Basic information about CAS 25526-93-6|Alovudine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Alovudine BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
5. Synonyms

Common Name	Alovudine
CAS Number	25526-93-6	Molecular Weight	244.22
Density	1.4±0.1 g/cm3	Boiling Point	/
Molecular Formula	C₁₀H₁₃FN₂O₄	Melting Point	176-178ºC(lit.)
MSDS	/	Flash Point	/

Names

Name	3'-Deoxy-3'-fluorothymidine
Synonym	More Synonyms

Alovudine BiologicalActivity

Description	3'-Fluoro-3'-deoxythymidine (Alovudine) is a marker of DNA synthesis that is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and thus is a better biomarker in pancreatic cancer[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Others >>Others
References	[1]. Challapalli A, et al. 3'-Deoxy-3'-¹⁸F-fluorothymidine positron emission tomography as an early predictor of disease progression in patients with advanced and metastatic pancreatic cancer. Eur J Nucl Med Mol Imaging. 2015 May;42(6):831-40.

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Melting Point	176-178ºC(lit.)
Molecular Formula	C₁₀H₁₃FN₂O₄
Molecular Weight	244.22
Exact Mass	244.085938
PSA	84.32000
LogP	-0.52
Index of Refraction	1.565
InChIKey	UXCAQJAQSWSNPQ-XLPZGREQSA-N
SMILES	Cc1cn(C2CC(F)C(CO)O2)c(=O)[nH]c1=O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XP2073000

CHEMICAL NAME :: Thymidine, 3'-deoxy-3'-fluoro-

CAS REGISTRY NUMBER :: 25526-93-6

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H13-F-N2-O4

MOLECULAR WEIGHT :: 244.25

WISWESSER LINE NOTATION :: T6NVMVJ E1 A- ET5OTJ B1Q CF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - mouse Ascites tumor

DOSE/DURATION :: 10 umol/L

REFERENCE :: PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 32,178,1977

Synonyms

MFCD00056058

3,-Deoxy-3,-fluoro Thymidine

Thymidine, 3'-deoxy-3'-fluoro-

Alovudine

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