CAS 3184-13-2|L(+)-Ornithine hydrochloride
| Common Name | L(+)-Ornithine hydrochloride | ||
|---|---|---|---|
| CAS Number | 3184-13-2 | Molecular Weight | 168.622 |
| Density | 1.57 | Boiling Point | 308.7ºC at 760 mmHg |
| Molecular Formula | C5H13ClN2O2 | Melting Point | 245 °C (dec.)(lit.) |
| MSDS | ChineseUSA | Flash Point | 140.5ºC |
Names
| Name | L(+)-Ornithine hydrochloride |
|---|---|
| Synonym | More Synonyms |
L(+)-Ornithine hydrochloride BiologicalActivity
| Description | L-Ornithine Hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen. |
|---|---|
| Related Catalog | Natural Products >>OthersResearch Areas >>Metabolic Disease |
| Target | Human Endogenous Metabolite |
| References | [1]. Demura S, et al. Effect of L-ornithine hydrochloride ingestion on intermittent maximal anaerobic cycle ergometer performance and fatigue recovery after exercise. Eur J Appl Physiol. 2011 Nov;111(11):2837-43. |
Chemical & Physical Properties
| Density | 1.57 |
|---|---|
| Boiling Point | 308.7ºC at 760 mmHg |
| Melting Point | 245 °C (dec.)(lit.) |
| Molecular Formula | C5H13ClN2O2 |
| Molecular Weight | 168.622 |
| Flash Point | 140.5ºC |
| Exact Mass | 168.066559 |
| PSA | 89.34000 |
| LogP | 1.33980 |
| Index of Refraction | 24 ° (C=4, 6mol/L HCl) |
| InChIKey | GGTYBZJRPHEQDG-WCCKRBBISA-N |
| SMILES | Cl.NCCCC(N)C(=O)O |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10 gm/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 62,49,1973 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4776 No. of Facilities: 162 (estimated) No. of Industries: 2 No. of Occupations: 6 No. of Employees: 2955 (estimated) No. of Female Employees: 2312 (estimated)
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | RM2985000 |
| HS Code | 2922499990 |
Preparation
Customs
| HS Code | 2922499990 |
|---|---|
| Summary | HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0% |
Articles48
More Articles| Increased ornithine-derived polyamines cause airway hyperresponsiveness in a mouse model of asthma. Am. J. Respir. Cell. Mol. Biol. 48(6) , 694-702, (2013) Up-regulation of arginase contributes to airways hyperresponsiveness (AHR) in asthma by reducing L-arginine bioavailability for the nitric oxide (NO) synthase isozymes. The product of arginase activit... | |
| Microbacterium kyungheense sp. nov. and Microbacterium jejuense sp. nov., isolated from salty soil. Int. J. Syst. Evol. Microbiol. 64(Pt 7) , 2267-73, (2014) Two novel strains, THG-C26(T) and THG-C31(T), were characterized using a polyphasic approach to determine their taxonomic positions. These two isolates were aerobic, Gram-stain-positive, non-motile, n... | |
| Treatment of arginase deficiency revisited: guanidinoacetate as a therapeutic target and biomarker for therapeutic monitoring. Dev. Med. Child Neurol. 56(10) , 1021-4, (2014) Hyperargininaemia is a disorder of the last step of the urea cycle. It is an autosomal recessive disease caused by deficiency of liver arginase-1 and usually presents later in childhood with progressi... |
Synonyms
| L-Ornithine, monohydrochloride |
| H-Orn-OH.HCl |
| L-Orn hydrochloride |
| (2S)-2,5-diaminopentanoic acid hydrochloride |
| L-Ornithine monohydrochloride |
| L-Ornithine HCl |
| (S)-2,5-Diaminovaleric acid monohydrochloride |
| D-ORNITHINE HCL |
| L(+)-Ornithinehydrochloride |
| H-Orn-OH·HCl |
| (S)-2,5-Diaminopentanoic acid monohydrochloride |
| D-ORN,HCL |
| MFCD00012917 |
| H-D-ORN HCL |
| L-ORN HCL |
| ORNITHINE HCL |
| L(+)-Ornithine Hydrochloride |
| L-Ornithine hydrochloride (1:1) |
| H-L-ORN-OH HCL |
| Z3YZVQ &&L or S Form HCl |
| (S)-(+)-2,5-Diaminopentanoic acid hydrochloride |
| H-D-ORN-OH HCL |
| (S)-2,5-Diaminopentanoic acid hydrochloride |
| L-Ornithine, hydrochloride (1:1) |
| EINECS 240-729-3 |
| L-ornithine hydrochloride |
| Guanine Hydrochloride |
