CAS 61-54-1|tryptamine
Introduction：Basic information about CAS 61-54-1|tryptamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | tryptamine | ||
|---|---|---|---|
| CAS Number | 61-54-1 | Molecular Weight | 160.216 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 378.8±0.0 °C at 760 mmHg |
| Molecular Formula | C10H12N2 | Melting Point | 113-116 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 187.7±8.1 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | tryptamine |
|---|---|
| Synonym | More Synonyms |
tryptamine BiologicalActivity
| Description | Tryptamine is a monoamine alkaloid, similar to other trace amines, is believed to play a role as a neuromodulator or neurotransmitter. |
|---|---|
| Related Catalog | Natural Products >>AlkaloidResearch Areas >>Others |
| Target | Human Endogenous Metabolite |
| References | [1]. Jones RS, et al. Tryptamine: a neuromodulator or neurotransmitter in mammalian brain? Prog Neurobiol. 1982;19(1-2):117-39. |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 378.8±0.0 °C at 760 mmHg |
| Melting Point | 113-116 °C(lit.) |
| Molecular Formula | C10H12N2 |
| Molecular Weight | 160.216 |
| Flash Point | 187.7±8.1 °C |
| Exact Mass | 160.100052 |
| PSA | 41.81000 |
| LogP | 1.38 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.669 |
| InChIKey | APJYDQYYACXCRM-UHFFFAOYSA-N |
| SMILES | NCCc1c[nH]c2ccccc12 |
| Water Solubility | negligible |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 223 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 66,1692,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 9,453,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- DPHFAK Dissertationes Pharmaceuticae et Pharmacologicae. (Warsaw, Poland) V.18-24, 1966-72. For publisher information, see PJPPAA. Volume(issue)/page/year: 22,313,1970
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
| Hazard Codes | Xi |
| Risk Phrases | 20/21/22-36/37/38-41-37/38-22 |
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | NL4020000 |
| HS Code | 29339990 |
Customs
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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| Enantioselective formal synthesis of ent-rhynchophylline and ent-isorhynchophylline. Chem. Commun. (Camb.) 49(19) , 1954-6, (2013) Starting from (S)-tryptophanol, a formal synthesis of ent-rhynchophylline and ent-isorhynchophylline, involving stereoselective cyclocondensation, spirocyclization, and alkylation reactions, and the f... | |
| A separation of tyramine on a 2-(4-methoxyphenyl)ethylamine imprinted polymer: an answer from theoretical and experimental studies. Talanta 129 , 155-64, (2014) A 2-(4-methoxyphenyl)ethylamine imprinted polymer (MIP) was successfully applied for the selective separation of tyramine. A computational analysis was used to predict the affinity of the polymer matr... |
Synonyms
| 2-(1H-Indol-3-yl)ethylamine |
| Tryptamine |
| 1H-Indole-3-ethanamine |
| 2-indol-3-yl-ethylamine |
| Indole-ethylamine |
| L-TRYPTAMINE |
| EINECS 200-510-5 |
| 2-Indol-3-yl-aethylamin |
| Tryptamin |
| 3-Indoleethanamine |
| 2-(1H-Indol-3-yl)ethanamine |
| MFCD00005661 |
| TRYPTAMINE(P) |
| T56 BMJ D2Z |
| [2-(1H-indol-3-yl)-ethyl]amine |
| TRIPTAMINE |
| (1H-indol-3-yl)ethanamine |
| 2-indol-3-ylethylamine |
