Introduction:Basic information about CAS 131265-35-5|8-Azido-2′-deoxyadenosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 8-Azido-2′-deoxyadenosine |
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| CAS Number | 131265-35-5 | Molecular Weight | 236.23 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C10H12N4O3 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 8-azido-2'-deoxyadenosine |
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| Synonym | More Synonyms |
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8-Azido-2′-deoxyadenosine BiologicalActivity
| Description | 8-Azido-2′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Molecular Formula | C10H12N4O3 |
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| Molecular Weight | 236.23 |
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| Exact Mass | 292.10300 |
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| PSA | 169.06000 |
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| LogP | 0.02496 |
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| InChIKey | CWYYTRHMNNPRNR-KVQBGUIXSA-N |
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| SMILES | [N-]=[N+]=Nc1nc2c(N)ncnc2n1C1CC(O)C(CO)O1 |
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Synonyms
| 8-Azido-1-p-menthen |
| 8-azido-2'deoxyadenosine |