Introduction：Basic information about CAS 25953-14-4|Thymidine,5'-deoxy-5'-iodo-, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Thymidine,5'-deoxy-5'-iodo- |
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| CAS Number | 25953-14-4 | Molecular Weight | 352.13 |
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| Density | 1.871g/cm3 | Boiling Point | / |
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| Molecular Formula | C10H13IN2O4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 5'-iodo-5'-deoxythymidine |
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| Synonym | More Synonyms |
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Thymidine,5'-deoxy-5'-iodo- BiologicalActivity
| Description | 5′-Deoxy-5′-iodothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.871g/cm3 |
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| Molecular Formula | C10H13IN2O4 |
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| Molecular Weight | 352.13 |
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| Exact Mass | 351.99200 |
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| PSA | 84.32000 |
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| Index of Refraction | 1.634 |
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| InChIKey | LEQXAJKTJWCXEC-XLPZGREQSA-N |
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| SMILES | Cc1cn(C2CC(O)C(CI)O2)c(=O)[nH]c1=O |
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Synonyms
| 5'-deoxy-5'-iodothymidine |
| 5'-iodo-5'-deoxy-thymidine |
| 5'-Jod-5'-desoxy-thymidin |
| 5'-Deoxy-5'-iodo-D-thymidine |
