CAS 1668-99-1|(9S)-6'-methoxycinchonan-9-ol monohydrochloride

Introduction：Basic information about CAS 1668-99-1|(9S)-6'-methoxycinchonan-9-ol monohydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Synonyms

Common Name	(9S)-6'-methoxycinchonan-9-ol monohydrochloride
CAS Number	1668-99-1	Molecular Weight	360.87800
Density	/	Boiling Point	495.9ºC at 760mmHg
Molecular Formula	C₂₀H₂₅ClN₂O₂	Melting Point	/
MSDS	/	Flash Point	253.7ºC

Names

Name	(S)-[(2R,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol,hydrochloride
Synonym	More Synonyms

Chemical & Physical Properties

Boiling Point	495.9ºC at 760mmHg
Molecular Formula	C₂₀H₂₅ClN₂O₂
Molecular Weight	360.87800
Flash Point	253.7ºC
Exact Mass	360.16000
PSA	45.59000
LogP	3.91310
Vapour Pressure	1.19E-10mmHg at 25°C
InChIKey	LBSFSRMTJJPTCW-VJAUXQICSA-N
SMILES	C=CC1CN2CCC1CC2C(O)c1ccnc2ccc(OC)cc12.Cl

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VA5750000

CHEMICAL NAME :: Quinidine, monohydrochloride

CAS REGISTRY NUMBER :: 1668-99-1

LAST UPDATED :: 199506

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C20-H24-N2-O2.Cl-H

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 263 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 27,589,1977

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 52,2797,1992

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 30 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 27,589,1977

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >125 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 52,2797,1992 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 600 mg/kg/4D-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 33,203,1995

Synonyms

Quinidine,monohydrochloride

EINECS 216-792-8

Chinidin hydrochlorid

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