CAS 4437-01-8|m-PEG7-alcohol

Introduction：Basic information about CAS 4437-01-8|m-PEG7-alcohol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Namem-PEG7-alcohol
CAS Number4437-01-8Molecular Weight340.410
Density1.1±0.1 g/cm3Boiling Point416.0±40.0 °C at 760 mmHg
Molecular FormulaC15H32O8Melting Point/
MSDS/Flash Point205.4±27.3 °C

Names

Name2,5,8,11,14,17,20-Heptaoxadocosan-22-ol
SynonymMore Synonyms

m-PEG7-alcohol BiologicalActivity

Descriptionm-PEG7-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

Density1.1±0.1 g/cm3
Boiling Point416.0±40.0 °C at 760 mmHg
Molecular FormulaC15H32O8
Molecular Weight340.410
Flash Point205.4±27.3 °C
Exact Mass340.209717
PSA84.84000
LogP-2.95
Vapour Pressure0.0±2.2 mmHg at 25°C
Index of Refraction1.449
InChIKeyAGWKUHGLWHMYTG-UHFFFAOYSA-N
SMILESCOCCOCCOCCOCCOCCOCCOCCO

Safety Information

WGK Germany3
HS Code2909499000

Customs

HS Code2909499000
Summary2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

Synonyms

2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
MFCD06201006
Heptaethylene Glycol MonoMethyl Ether
2,5,8,11,14,17,20-Heptaoxadocosan-22-ol
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