CAS 39665-12-8|L(+)-Lysine monohydrate
| Common Name | L(+)-Lysine monohydrate | ||
|---|---|---|---|
| CAS Number | 39665-12-8 | Molecular Weight | 164.20300 |
| Density | / | Boiling Point | 400ºC at 760 mmHg |
| Molecular Formula | C6H16N2O3 | Melting Point | 212-214 °C |
| MSDS | USA | Flash Point | 195.7ºC |
Names
| Name | L(+)-Lysine monohydrate |
|---|---|
| Synonym | More Synonyms |
L(+)-Lysine monohydrate BiologicalActivity
| Description | L-Lysine hydrate is an essential amino acid. L-Lysine hydrate can be research for vascular calcification (VC) and acute pancreatitis[1][2]. |
|---|---|
| Related Catalog | Research Areas >>OthersResearch Areas >>Inflammation/Immunology |
| Target | Microbial Metabolite Human Endogenous Metabolite |
| In Vitro | L-Lysine hydrate (VSMCs) suppresses plasma iPTH and elevates plasma alanine, proline, plasma arginine, and homo arginine, thereby inhibiting apoptosis of VSMCs and mineral precipitation[1]. |
| In Vivo | L-Lysine hydrate (40 μg/kg; p.o.) ameliorates arterial calcification in adenine rats and protects the femora from osteoporotic changes in adenine rats[1]. L-Lysine hydrate (10 and 400 mg/kg; i.g. and p.o.; Male mice) inhibits pancreatic tissue damage[2]. Animal Model: Male mice[2] Dosage: 10 and 400 mg/kg Administration: Intraperitoneal injection and oral administration; for 15 days Result: Inhibited the release of the inflammatory cytokine IL-6 and enhance antioxidant activity. |
| References | [1]. Shimomura A, et, al. Dietary L-lysine prevents arterial calcification in adenine-induced uremic rats. J Am Soc Nephrol. 2014 Sep;25(9):1954-65. [2]. Al-Malki AL. Suppression of acute pancreatitis by L-lysine in mice. BMC Complement Altern Med. 2015 Jun 23;15:193. |
Chemical & Physical Properties
| Boiling Point | 400ºC at 760 mmHg |
|---|---|
| Melting Point | 212-214 °C |
| Molecular Formula | C6H16N2O3 |
| Molecular Weight | 164.20300 |
| Flash Point | 195.7ºC |
| Exact Mass | 164.11600 |
| PSA | 98.57000 |
| LogP | 0.86360 |
| InChIKey | HZRUTVAFDWTKGD-JEDNCBNOSA-N |
| SMILES | NCCCCC(N)C(=O)O.O |
| Water Solubility | >1500 g/L (20 ºC) |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | OL5540000 |
| HS Code | 2922411000 |
Customs
| HS Code | 2922499990 |
|---|---|
| Summary | HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0% |
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| A new antitumor enzyme, L-lysine alpha-oxidase from Trichoderma viride. Purification and enzymological properties. J. Biol. Chem. 255 , 976, (1980) L-Lysine alpha-oxidase from Trichoderma viride Y244-2 has been purified to homogeneity. The enzyme shows absorption maxima at 277, 388, and 466 nm and a shoulder around 490 nm and contains 2 mol of FA... | |
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Synonyms
| L-Lysine monohydrate |
| L-Lysine hydrate |
| lysine,hydrate |
| L-LYS H2O |
| LYS,MONOHYDRATE |
| EINECS 200-294-2 |
| H-Lys-OH H2O |
| MFCD00151035 |
