Introduction：Basic information about CAS 138831-86-4|OVA Peptide 257-264, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | OVA Peptide 257-264 |
|---|
| CAS Number | 138831-86-4 | Molecular Weight | 963.12800 |
|---|
| Density | / | Boiling Point | / |
|---|
| Molecular Formula | C45H74N10O13 | Melting Point | / |
|---|
| MSDS | ChineseUSA | Flash Point | / |
|---|
Names
| Name | h-ser-ile-ile-asn-phe-glu-lys-leu-oh |
|---|
| Synonym | More Synonyms |
|---|
OVA Peptide 257-264 BiologicalActivity
| Description | OVA Peptide (257-264) is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb. |
|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>OthersPeptides |
|---|
| In Vitro | TAP1-I- and C57BL/6 macrophages may process Crl-OVA and full-length OVA in different cellular compartments and that the protein context of the OVA Peptide (257-264) epitope influences the extent of TAP-independent processing for MHC class I presentation. OVA Peptide (257-264) epitope is presented with a differential dependence on the TAP transporter depending on the protein context of the OVA epitope: OVA Peptide (257-264) contained within the MBPCrl-OVA or Crl-OVA bacterial fusion proteins is presented with little dependence on the TAP transporter, while OVA Peptide (257-264) contained within full-length ovalbumin is largely dependent on the TAP transporter, regardless of whether recombinant OVA is expressed in bacteria or the native protein is coupled to polystyrene beads[1]. |
|---|
| Cell Assay | TAPl-/- or C57BL/6 macrophages are co-incubated with either bacteria or polystyrene beads containing the 257-264 epitope from ovalbumin [OVA Peptide (257-264)], which binds the mouse class I molecule Kb. The source of the OVA(257-264) epitope is either the Crl-OVA(257-264) (Crl-OVA) fusion protein, the maltose binding protein (MBP)-Crl-OVA fusion protein, native OVA or bacterial recombinant OVA (rOVA); Crl-OVA, MBP-Crl-OVA and rOVA are each expressed in bacteria, and Crl-OVA and MBP-Crl-OVA purified from bacterial lysates and native egg OVA are coated onto polystyrene beads[1]. |
|---|
| References | [1]. Wick MJ, et al. Major histocompatibility complex class I presentation of ovalbumin peptide 257-264 from exogenous sources: protein context influences the degree of TAP-independent presentation. Eur J Immunol. 1996 Nov;26(11):2790-9. |
|---|
Chemical & Physical Properties
| Molecular Formula | C45H74N10O13 |
|---|
| Molecular Weight | 963.12800 |
|---|
| Exact Mass | 962.54400 |
|---|
| PSA | 393.66000 |
|---|
| LogP | 2.87160 |
|---|
| InChIKey | JVJGCCBAOOWGEO-RUTPOYCXSA-N |
|---|
| SMILES | CCC(C)C(NC(=O)C(N)CO)C(=O)NC(C(=O)NC(CC(N)=O)C(=O)NC(Cc1ccccc1)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)O)C(C)CC |
|---|
| Storage condition | 2-8℃ |
|---|
Synonyms
| Ovalbumin (257-264) chicken |
| OVALBUMIN(257-264) ANTIGEN PEPTIDE |
| OVA PEPTIDE (257-264) |
| SIINFEKL |
| CHICKEN OVALBUMIN FRAGMENT (257-264) |
| SER-ILE-ILE-ASN-PHE-GLU-LYS-LEU |
| OVA (257-264) (CHICKEN) |
| H2N-SIINFEKL-OH |
| OVA (257-264) |
| OVALBUMIN (257-264) (CHICKEN) |
