Introduction：Basic information about CAS 1668-85-5|Epi-galantamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Epi-galantamine |
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| CAS Number | 1668-85-5 | Molecular Weight | 287.35400 |
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| Density | 1.28g/cm3 | Boiling Point | 439.3ºC at 760 mmHg |
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| Molecular Formula | C17H21NO3 | Melting Point | 183-185ºC |
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| MSDS | / | Flash Point | 219.5ºC |
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Names
| Name | Epi Galanthamine |
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| Synonym | More Synonyms |
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Epi-galantamine BiologicalActivity
| Description | Epi-galantamine is a diastereomer of Galantamine. Epi-galantamine is an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus woronowii). Epi-galantamine inhibits AChE with an EC50 of 45.7 μM[1][2][3]. |
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| Related Catalog | Research Areas >>Neurological DiseaseSignaling Pathways >>Neuronal Signaling >>AChE |
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| Target | EC50: 45.7 μM (AChE)[1] |
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| References | [1]. Thomsen T, et al. Stereoselectivity of cholinesterase inhibition by galanthamine and tolerance in humans. Eur J Clin Pharmacol. 1990;39(6):603-5. [2]. Berkov S, et al. Rapid TLC/GC-MS identification of acetylcholinesterase inhibitors in alkaloid extracts. Phytochem Anal. 2008 Sep-Oct;19(5):411-9. [3]. Maláková J, et al. High-performance liquid chromatographic method with UV photodiode-array, fluorescence and mass spectrometric detection for simultaneous determination of galantamine and its phase I metabolites in biological samples. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Jun 15;853(1-2):265-74. |
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Chemical & Physical Properties
| Density | 1.28g/cm3 |
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| Boiling Point | 439.3ºC at 760 mmHg |
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| Melting Point | 183-185ºC |
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| Molecular Formula | C17H21NO3 |
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| Molecular Weight | 287.35400 |
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| Flash Point | 219.5ºC |
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| Exact Mass | 287.15200 |
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| PSA | 41.93000 |
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| LogP | 1.78820 |
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| Vapour Pressure | 1.71E-08mmHg at 25°C |
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| Index of Refraction | 1.636 |
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| InChIKey | ASUTZQLVASHGKV-IFIJOSMWSA-N |
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| SMILES | COc1ccc2c3c1OC1CC(O)C=CC31CCN(C)C2 |
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| Storage condition | -20°C |
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Safety Information
Synonyms
