Introduction：Basic information about CAS 132172-61-3|DOTAP chloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | DOTAP chloride |
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| CAS Number | 132172-61-3 | Molecular Weight | 663.08900 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C42H80ClNO4 | Melting Point | 35-38ºC |
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| MSDS | ChineseUSA | Flash Point | / |
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Names
| Name | 2,3-di(octadec-9-enoyloxy)propyl-trimethylazanium |
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| Synonym | More Synonyms |
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DOTAP chloride BiologicalActivity
| Description | DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| Target | IC50: Cationic Lipid[1] |
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| In Vitro | liposomes are reorganized by associating with DNA. The transfection efficiency of DOTAP liposomes is mainly influenced by lipid composition and cell type, but not by size or zeta potential[1]. |
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| References | [1]. Kim BK, et al. DOTAP/DOPE ratio and cell type determine transfection efficiency with DOTAP-liposomes.Biochim Biophys Acta. 2015 Oct;1848(10 Pt A):1996-2001. |
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Chemical & Physical Properties
| Melting Point | 35-38ºC |
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| Molecular Formula | C42H80ClNO4 |
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| Molecular Weight | 663.08900 |
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| Exact Mass | 662.60900 |
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| PSA | 52.60000 |
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| LogP | 12.22260 |
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| InChIKey | KSXTUUUQYQYKCR-LQDDAWAPSA-M |
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| SMILES | CCCCCCCCC=CCCCCCCCC(=O)OCC(C[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC.[Cl-] |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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Articles1
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Synonyms
| 2,3-dioleyloxypropyltrimethylammonium chloride |
| 1,2-dioleoyl-3-trimethylammonium-propane chloride |
| 1,2-dioleoyl-3-trimethylammonium-propane chloride salt |
| DOTAP chloride |
