CAS 163158-19-8|MOG (35-55), human

Introduction：Basic information about CAS 163158-19-8|MOG (35-55), human, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. MOG (35-55), human BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	MOG (35-55), human
CAS Number	163158-19-8	Molecular Weight	2591.99000
Density	/	Boiling Point	/
Molecular Formula	C₁₂₀H₁₇₉N₃₅O₂₈S	Melting Point	/
MSDS	USA	Flash Point	/

Names

Name	h-met-glu-val-gly-trp-tyr-arg-pro-pro-phe-ser-arg-val-val-his-leu-tyr-arg-asn-gly-lys-oh
Synonym	More Synonyms

MOG (35-55), human BiologicalActivity

Description	MOG (35-55), human is a component of CNS myelin. MOG (35-55), human is different from mMOG (35-55) by a proline for serine substitution at position 42. MOG (35-55), human is also immunogenic, but not encephalitogenic, and is only partially cross-reactive with mMOG35–55. MOG (35-55), human induces minimal clinical signs of EAE relative to the rodent peptide[1].
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease
References	[1]. Cathleen Rich, et al. Myelin oligodendrocyte glycoprotein-35-55 peptide induces severe chronic experimental autoimmune encephalomyelitis in HLA-DR2-transgenic mice. Eur J Immunol. 2004 May;34(5):1251-61. [2]. Alfred R Oliver, et al.Rat and human myelin oligodendrocyte glycoproteins induce experimental autoimmune encephalomyelitis by different mechanisms in C57BL/6 mice. J Immunol. 2003 Jul 1;171(1):462-8.

Description

MOG (35-55), human is a component of CNS myelin. MOG (35-55), human is different from mMOG (35-55) by a proline for serine substitution at position 42. MOG (35-55), human is also immunogenic, but not encephalitogenic, and is only partially cross-reactive with mMOG35–55. MOG (35-55), human induces minimal clinical signs of EAE relative to the rodent peptide[1].

Related Catalog

Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease

References

[1]. Cathleen Rich, et al. Myelin oligodendrocyte glycoprotein-35-55 peptide induces severe chronic experimental autoimmune encephalomyelitis in HLA-DR2-transgenic mice. Eur J Immunol. 2004 May;34(5):1251-61.

[2]. Alfred R Oliver, et al.Rat and human myelin oligodendrocyte glycoproteins induce experimental autoimmune encephalomyelitis by different mechanisms in C57BL/6 mice. J Immunol. 2003 Jul 1;171(1):462-8.

Chemical & Physical Properties

Molecular Formula	C₁₂₀H₁₇₉N₃₅O₂₈S
Molecular Weight	2591.99000
Exact Mass	2590.34000
PSA	1050.31000
LogP	6.20280
InChIKey	JZTWEKCSWFQBIT-UHFFFAOYSA-N
SMILES	CSCCC(N)C(=O)NC(CCC(=O)O)C(=O)NC(C(=O)NCC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCCNC(=N)N)C(=O)N1CCCC1C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(=O)NC(C(=O)NC(Cc1c[nH]cn1)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(N)=O)C(=O)NCC(=O)NC(CCCCN)C(=O)O)C(C)C)C(C)C)C(C)C

Synonyms

h2n-mevgwyrppfsrvvhlyrngk-oh

myelin oligodendrocyte glycoprotein precursor

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