CAS 16721-80-5|Sodium hydrosulfide

CHEMICAL IDENTIFICATION

RTECS NUMBER :

WE1900000

CHEMICAL NAME :

Sodium sulfide

CAS REGISTRY NUMBER :

16721-80-5

LAST UPDATED :

199710

DATA ITEMS CITED :

12

MOLECULAR FORMULA :

H-Na-S

MOLECULAR WEIGHT :

56.06

WISWESSER LINE NOTATION :

.NA..S H

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

14600 ug/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

18 mg/kg

TOXIC EFFECTS :

Behavioral - coma

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

200 mg/kg

TOXIC EFFECTS :

Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Lungs, Thorax, or Respiration - respiratory stimulation Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

67500 ug/kg/3D-I

TOXIC EFFECTS :

Brain and Coverings - other degenerative changes Biochemical - Metabolism (Intermediary) - amino acids (including renal excretion)

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

35 mg/kg/5D-I

TOXIC EFFECTS :

Brain and Coverings - other degenerative changes Biochemical - Metabolism (Intermediary) - amino acids (including renal excretion)

TYPE OF TEST :

Sex chromosome loss and nondisjunction

MUTATION DATA

TEST SYSTEM :

Insect - Drosophila melanogaster

DOSE/DURATION :

2000 ppm

REFERENCE :

ACBIEF Actualidades Biologicas (Medellin, Colombia). (Universidad de Antioquia, Departamento de Biologia, Apartado Aereo 1226, Medellin, Colombia) V.1- 1972- Volume(issue)/page/year: 14(52),48,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83515 No. of Facilities: 94 (estimated) No. of Industries: 5 No. of Occupations: 10 No. of Employees: 359 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83515 No. of Facilities: 577 (estimated) No. of Industries: 18 No. of Occupations: 34 No. of Employees: 12517 (estimated) No. of Female Employees: 4278 (estimated)