CAS 1646-88-4|Aldicarb (sulfone)

Introduction：Basic information about CAS 1646-88-4|Aldicarb (sulfone), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Aldicarb (sulfone) BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Customs
7. Articles17
8. Synonyms

Common Name	Aldicarb (sulfone)
CAS Number	1646-88-4	Molecular Weight	222.262
Density	1.2±0.1 g/cm3	Boiling Point	/
Molecular Formula	C₇H₁₄N₂O₄S	Melting Point	132-135ºC
MSDS	ChineseUSA	Flash Point	/
Symbol	GHS06, GHS09	Signal Word	Danger

Names

Name	aldoxycarb
Synonym	More Synonyms

Aldicarb (sulfone) BiologicalActivity

Description	Aldicarb sulfone(Temik sulfone) is a carbamate insecticide; is a cholinesterase inhibitor which prevents the breakdown of acetylcholine in the synapse.
Related Catalog	Signaling Pathways >>Neuronal Signaling >>AChEResearch Areas >>Others

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Melting Point	132-135ºC
Molecular Formula	C₇H₁₄N₂O₄S
Molecular Weight	222.262
Exact Mass	222.067429
PSA	93.21000
LogP	-0.57
Index of Refraction	1.495
InChIKey	YRRKLBAKDXSTNC-WEVVVXLNSA-N
SMILES	CNC(=O)ON=CC(C)(C)S(C)(=O)=O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UE2080000

CHEMICAL NAME :: Propionaldehyde, 2-methyl-2-(methylsulfonyl)-, O-(methylcarbamoyl)oxime

CAS REGISTRY NUMBER :: 1646-88-4

LAST UPDATED :: 199710

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C7-H14-N2-O4-S

MOLECULAR WEIGHT :: 222.29

WISWESSER LINE NOTATION :: WS1&X1&1&1UNN1&VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 20 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: FYI-OTS-0885-0443

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 140 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,18,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: SPEADM Special Publication of the Entomological Society of America. (4603 Calvert Rd., College Park, MD 20740) Volume(issue)/page/year: 78-1,61,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 21 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: FYI-OTS-0885-0443

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 14900 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: FYI-OTS-0885-0443

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C14,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - duck

DOSE/DURATION :: 33500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,18,1991

Safety Information

Symbol	GHS06, GHS09
Signal Word	Danger
Hazard Statements	H300-H310-H330-H400
Precautionary Statements	P260-P264-P273-P280-P284-P302 + P350
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T+: Very toxic;
Risk Phrases	24-26/28
Safety Phrases	S28;S45;S36/S37
RIDADR	UN 2757
RTECS	UE2080000
Packaging Group	I
Hazard Class	6.1(a)
HS Code	2930909052

Customs

HS Code	2930909052
Summary	2930909052 (e)-2-methyl-2-(methylsulfonyl)propanal o-methylcarbamoyl oxime。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:0.0%。MFN tarrif:6.5%。general tariff:30.0%

Articles17

Determination of pesticides in soy-based infant formula using liquid chromatography with electrospray ionization tandem mass spectrometry.

J. AOAC Int. 89(1) , 214-24, (2006)

A sensitive method using liquid chromatography with electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS) was developed and validated to quantify and confirm 13 pesticides, including aldicar...

Persistence and metabolism of aldicarb in fresh potatoes.

Bull. Environ. Contam. Toxicol. 32(3) , 274-81, (1984)

[Gas chromatographic analysis of aldicarb and its metabolites in urine].

Zhonghua Yu Fang Yi Xue Za Zhi 25(3) , 136-8, (1991)

A method is described for the analysis of aldicarb and its metabolites in urine by GC/FPD. The sample was concentrated with activated charcoal-Florisil column chromatography, eluted by dichloromethane...

Synonyms

2-methyl-2-(methylsulfonyl)propanal O-[(methylamino)carbonyl]oxime

(5Ξ)-7,7-dimethyl-8,8-dioxo-4-oxa-8λ6-thia-2,5-diazanon-5-en-3-one

[(E)-(2-methyl-2-methylsulfonylpropylidene)amino] N-methylcarbamate

MFCD00041804

EINECS 216-710-0

Aldicarb Sulfone

Propanal, 2-methyl-2-(methylsulfonyl)-, O-[(methylamino)carbonyl]oxime

aldoxycarb

(EZ)-2-mesyl-2-methylpropionaldehyde O-methylcarbamoyloxime

7,7-Dimethyl-4-oxa-8-thia-2,5-diazanon-5-en-3-one 8,8-dioxide

Aldicarb (sulfone)

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