CAS 138-55-6|picrocrocin

Introduction：Basic information about CAS 138-55-6|picrocrocin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Namepicrocrocin
CAS Number138-55-6Molecular Weight330.37300
Density1.31g/cm3Boiling Point520.4ºC at 760mmHg
Molecular FormulaC16H26O7Melting Point196 ºC (ethyl acetate )
MSDS/Flash Point187.1ºC

Names

Namepicrocrocin
SynonymMore Synonyms

picrocrocin BiologicalActivity

DescriptionPicrocrocin, an apocarotenoid found in the flowers of Cochliobolus sativus. Picrocrocin shows anticancer effect. Picrocrocin exhibits growth inhibitory effects against SKMEL-2 human malignant melanoma cells[1].
Related CatalogSignaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cancer
In VitroPicrocrocin exerted growth inhibitory effects on the SK-MEL-2 melanoma cells. The IC50 of picrocrocin against the SK-MEL-2 cells was 20 μM at 24-h incubation. The antiproliferative activity of picrocrocin was due to apoptosis and cell cycle arrest. In addition, picrocrocin enhanced the ROS levels and decreased the MMP levels of SK-MEL-2 cells. Finally, picrocrocin inhibited the JAK/STAT5 signalling pathway in the SK-MEL-2 melanoma cells[1].
References

[1]. Yu L, et al. Picrocrocin exhibits growth inhibitory effects against SKMEL- 2 human malignant melanoma cells by targeting JAK/ STAT5 signaling pathway, cell cycle arrest and mitochondrial mediated apoptosis. J BUON. 2018 Jul-Aug;23(4):1163-1168.

Chemical & Physical Properties

Density1.31g/cm3
Boiling Point520.4ºC at 760mmHg
Melting Point196 ºC (ethyl acetate )
Molecular FormulaC16H26O7
Molecular Weight330.37300
Flash Point187.1ºC
Exact Mass330.16800
PSA116.45000
Vapour Pressure5.27E-13mmHg at 25°C
Index of Refraction1.561
InChIKeyWMHJCSAICLADIN-WYWSWGBSSA-N
SMILESCC1=C(C=O)C(C)(C)CC(OC2OC(CO)C(O)C(O)C2O)C1
Water SolubilitySparingly soluble (24 g/L) (25 ºC)

Synonyms

saffron-bitter
Picrocrocine
(4R)-2,6,6-trimethyl-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxycyclohexene-1-carbaldehyde
CAS 443955-57-5|6-[[[1-[(2R)-2-Hydroxy-2-(6-methoxy-1,5-naphthyridin-4-yl)ethyl]-4-piperidinyl]amino
CAS 919747-36-7|N-(5-methyl-1,3-thiazol-2-yl)-2-(4-oxo-1,2,3-benzotriazin-3(4H)-yl)acetamide
Recommended......
CAS 13480-95-0|2-ETHYLTHIO-5-M CAS 13436-46-9|2-ETHOXYTETRAHY CAS 136773-58-5|1-[2-nitro-4-( CAS 1323-65-5|Dinonyl phenol CAS 13037-55-3|4-Thiazolidinon CAS 13122-97-9|Z-Ala-Tyr-OH CAS 13798-75-9|Boc-Asp(OBzl)-O CAS 13292-45-0|Rifamycin,3-[(1 CAS 13959-97-2|2-(diethoxymeth CAS 137218-25-8|2-Triflnoromet CAS 138154-39-9|C-1311 CAS 131179-95-8|Efaproxiral CAS 13505-34-5|heptane-2,6-dio CAS 13389-88-3|TETRAHYDRO-5-OX CAS 137588-59-1|(-)-(1S,4R)-N- CAS 131747-42-7|6-(Trifluorome CAS 13057-65-3|2-hydroxy-3-(2- CAS 132424-10-3|N-Methyl-3-phe CAS 132330-98-4|3-(Benzyloxy)- CAS 131513-35-4|3,4-DIHYDRO-3-
Disclaimer

This site is a non-commercial website, not accept any sponsorship and advertising. The content is collated from the Internet, does not represent the position of this site, for personal reference only, please distinguish by yourself! The belongs to the original author.

Copyright © 2025 All Rights Reserved.

TOP